The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: implications for irreversible stimulation of DNA cleavage.
about
Differential targeting of unpaired bases within duplex DNA by the natural compound clerocidin: a valuable tool to dissect DNA secondary structureExploiting bacterial DNA gyrase as a drug target: current state and perspectives.Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest.Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action.Concerted bis-alkylating reactivity of clerocidin towards unpaired cytosine residues in DNA.Cytotoxic and DNA-damaging effects of diterpenoid quinones from the roots of Salvia officinalis L. on colonic and hepatic human cells cultured in vitro.Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage.Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage.Direct and Topoisomerase II Mediated DNA Damage by Bis-3-chloropiperidines: The Importance of Being an Earnest G.
P2860
Q28484656-25B2ACB8-AAF9-4A28-9FDE-CE3441511E14Q34214929-3BEB32CE-FE9A-49DC-80D3-03790D0D7ADDQ38495295-E3DA20C6-EA99-4024-81A8-CD222D6F16DAQ39958978-729A6798-F63B-4A79-AF3F-FD3883F07384Q40250218-0D3FB0C5-0643-4C3E-BA28-FB953935B1A6Q40540102-CB3B2B6E-B8A7-47D6-8AFE-CB1FE2A682D0Q42264322-A0EF12DA-07D7-4E73-BDF8-D6FA583BB53BQ42872445-C4F35B45-22F2-4BF4-B4E8-217362F96772Q48100249-9A0C78FF-F1E8-40F9-BF2E-459C70923BBD
P2860
The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: implications for irreversible stimulation of DNA cleavage.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
The topoisomerase II poison cl ...... e stimulation of DNA cleavage.
@en
The topoisomerase II poison cl ...... e stimulation of DNA cleavage.
@nl
type
label
The topoisomerase II poison cl ...... e stimulation of DNA cleavage.
@en
The topoisomerase II poison cl ...... e stimulation of DNA cleavage.
@nl
prefLabel
The topoisomerase II poison cl ...... e stimulation of DNA cleavage.
@en
The topoisomerase II poison cl ...... e stimulation of DNA cleavage.
@nl
P2093
P2860
P356
P1476
The topoisomerase II poison cl ...... e stimulation of DNA cleavage.
@en
P2093
P2860
P304
P356
10.1093/NAR/29.20.4224
P407
P577
2001-10-01T00:00:00Z