Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level.

Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level.

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http://www.wikidata.org/entity/Q39309731
Alpha-synuclein and tau: teammates in neurodegeneration?Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathiesModelling Ser129 phosphorylation inhibits membrane binding of pore-forming alpha-synuclein oligomersRoles of tau protein in health and disease.Iron is a specific cofactor for distinct oxidation- and aggregation-dependent Aβ toxicity mechanisms in a Drosophila model.The importance of tau phosphorylation for neurodegenerative diseasesNon-targeted identification of prions and amyloid-forming proteins from yeast and mammalian cells.Untangling a role for tau in synucleinopathies.Biological metals and metal-targeting compounds in major neurodegenerative diseases.Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome.Cathepsin S increases tau oligomer formation through limited cleavage, but only IL-6, not cathespin S serum levels correlate with disease severity in the neurodegenerative tauopathy progressive supranuclear palsy.Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy.Neuroimmune Tau Mechanisms: Their Role in the Progression of Neuronal Degeneration.Aluminum and Alzheimer's Disease.Protein Co-Aggregation Related to Amyloids: Methods of Investigation, Diversity, and Classification
P2860

Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level.

Item
http://www.wikidata.org/entity/Q39309731
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Synergistic influence of phosp ...... at the single molecule level.
@en
Synergistic influence of phosp ...... at the single molecule level.
@nl
type
label
Synergistic influence of phosp ...... at the single molecule level.
@en
Synergistic influence of phosp ...... at the single molecule level.
@nl
prefLabel
Synergistic influence of phosp ...... at the single molecule level.
@en
Synergistic influence of phosp ...... at the single molecule level.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P478
P50
P577
P5875
P6179
P698
P921
P932
P356
P1433
P1476
Synergistic influence of phosp ...... at the single molecule level.
@en
P2093
P2860
P2888
P304
P31
P356
P478
P50
P577
P5875
P6179
P698
P921
P932