Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
about
The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1aThe tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) 1a by increasing its apparent H+ affinityInteraction of acid-sensing ion channel (ASIC) 1 with the tarantula toxin psalmotoxin 1 is state dependentASICs and cardiovascular homeostasisStructure and activity of the acid-sensing ion channelsPore architecture and ion sites in acid-sensing ion channels and P2X receptorsAcid-sensing ionic channels in the rat vestibular endorgans and gangliaSelective regulation of acid-sensing ion channel 1 by serine proteasesTRPA1 is a major oxidant sensor in murine airway sensory neuronsA single amino acid tunes Ca2+ inhibition of brain liver intestine Na+ channel (BLINaC)Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNSPresynaptic external calcium signaling involves the calcium-sensing receptor in neocortical nerve terminalsCellular and Molecular Mechanisms of PainA combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a.Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line.Effect of deep tissue incision on pH responses of afferent fibers and dorsal root ganglia innervating muscleAcid-Sensing Ion Channels and PainProtons and Psalmotoxin-1 reveal nonproton ligand stimulatory sites in chicken acid-sensing ion channel: Implication for simultaneous modulation in ASICs.Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR.Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cellsExtracellular chloride modulates the desensitization kinetics of acid-sensing ion channel 1a (ASIC1a)High-density expression of Ca2+-permeable ASIC1a channels in NG2 glia of rat hippocampus.P2X2/3 and P2X3 receptors contribute to the metaboreceptor component of the exercise pressor reflex.Degenerin sites mediate proton activation of deltabetagamma-epithelial sodium channel.Femoral artery occlusion increases expression of ASIC3 in dorsal root ganglion neuronsASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domainConformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation.Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosisA TRPA1-dependent mechanism for the pungent sensation of weak acids.Acid-sensitive ion channels and receptorsExpression and activity of acid-sensing ion channels in the mouse anterior pituitary.Computational Tools for Interpreting Ion Channel pH-Dependence.Effect of Intramuscular Protons, Lactate, and ATP on Muscle Hyperalgesia in Rats.ENaCs and ASICs as therapeutic targets.Highly conserved salt bridge stabilizes rigid signal patch at extracellular loop critical for surface expression of acid-sensing ion channels.Non-selective cation channels, transient receptor potential channels and ischemic stroke.ASIC3 channels in multimodal sensory perceptionCysteine 149 in the extracellular finger domain of acid-sensing ion channel 1b subunit is critical for zinc-mediated inhibition.TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations.Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions.
P2860
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P2860
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
@en
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
@nl
type
label
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
@en
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
@nl
prefLabel
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
@en
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
@nl
P1433
P1476
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.
@en
P2093
David C Immke
Edwin W McCleskey
P356
10.1016/S0896-6273(02)01130-3
P407
P577
2003-01-01T00:00:00Z