The N-terminal domain of p73 interacts with the CH1 domain of p300/CREB binding protein and mediates transcriptional activation and apoptosis.
about
NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycleASPP1 and ASPP2: common activators of p53 family membersInhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylationSSRP1 functions as a co-activator of the transcriptional activator p63Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionRegulation of transcription of the human presenilin-1 gene by ets transcription factors and the p53 protooncogeneMDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylationPhosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cellsBeta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2E1A activates transcription of p73 and Noxa to induce apoptosisInteraction between the HPV E7 oncoprotein and the transcriptional coactivator p300Function of p73, not of p53, is inhibited by the physical interaction with RACK1 and its inhibitory effect is counteracted by pRB.p73 Interacts with human immunodeficiency virus type 1 Tat in astrocytic cells and prevents its acetylation on lysine 28.Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function.p53 Family and Cellular Stress Responses in Cancer.MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins.Regulation of p73 activity by post-translational modifications.Interplay between TAp73 Protein and Selected Activator Protein-1 (AP-1) Family Members Promotes AP-1 Target Gene Activation and Cellular Growth.p73, a sophisticated p53 family member in the cancer world.Cataloging and organizing p73 interactions in cell cycle arrest and apoptosisDirect activation of forkhead box O3 by tumor suppressors p53 and p73 is disrupted during liver regeneration in mice.Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation.Role of activating transcription factor 3 on TAp73 stability and apoptosis in paclitaxel-treated cervical cancer cells.The p53 family and programmed cell deathLysine-specific modifications of p53: a matter of life and death?Role of the p53-homologue p73 in E2F1-induced apoptosis.Characterization of the new human pleomorphic undifferentiated sarcoma TP53-null cell line mfh-val2.p73-Binding Partners and Their Functional Significance.FGF8, c-Abl and p300 participate in a pathway that controls stability and function of the ΔNp63α protein.Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibition.Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress.A new coactivator function for Zac1's C2H2 zinc finger DNA-binding domain in selectively controlling PCAF activity.TIP60 represses transcriptional activity of p73beta via an MDM2-bridged ternary complex.Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis.TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones.A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells.p19ras interacts with and activates p73 by involving the MDM2 protein.p300 regulates p63 transcriptional activity.The C-terminal sterile alpha motif and the extreme C terminus regulate the transcriptional activity of the alpha isoform of p73.Identification of protein kinase A catalytic subunit beta as a novel binding partner of p73 and regulation of p73 function.
P2860
Q24298090-AD6AA396-F526-4841-B615-CE3497591370Q24305256-312E5BEA-DE8F-47D2-9A22-BD837B4DA17CQ24305405-57CB9966-29F0-4952-82A1-595FB3B34DB3Q24534925-9C0A4BA1-1E34-4030-B1E1-0474FC54BBD0Q24562892-33094C3F-1B3F-42E2-9E74-BBEFB0EF28C7Q28143662-E03332CE-4408-4068-B811-08D9A3EBE30CQ28204918-589FCED1-2DED-4453-9073-23436041B197Q28207530-C8149363-777D-43D7-98C4-AECFACCD8FDCQ28218131-C9C6E1A2-7BF1-4ED2-BCA6-F5A47BF71091Q28295846-2EF44FAA-12A0-4ED5-941B-D19134F3EC29Q28566098-2917AF43-4D67-474F-A3E1-00767D2BAF64Q30936349-5FFB60A6-60E5-4C78-B0B0-9C8840D4B7CFQ33292132-B2D40A1F-9E60-4381-91C9-81412F3795B1Q34114100-079F1069-3BB1-454A-BB95-F03C27FFBCC6Q34377287-794B455F-E2E1-42B1-A647-B93D621D4B29Q35817339-CF897D84-1B8C-4150-BC24-75068816C111Q35865249-3709B993-1A4A-4A8A-A8DD-9EB74C254168Q35883861-9F0829ED-B62D-4FAE-81C5-A630C036E7B8Q36306728-BC86E33E-B1D1-4204-8401-F9B7B70B2998Q36859304-089C151F-FFF7-4087-9EF2-7B4CEE82C978Q37089152-21CD045E-3900-42D5-8810-FB19049D48D1Q37117547-F6718B59-B100-4030-A352-358E3B11B508Q37198034-93C4C473-CF14-41C9-BD72-6631CE127ECBQ37310208-07BCDC95-6C9C-4965-8784-B503B4719CF7Q38168223-0AE9C153-AAA5-4927-83A7-A5046C80BDA4Q38306110-DE69740B-8764-4C4C-902A-BDD427C69C7CQ38698137-7E87B646-7671-401E-98CE-8F79A11A3B38Q38731186-32348CAB-6D39-4A1C-9094-1C0D1B3064ABQ38882470-114189FE-4C1F-4DB2-ACB3-036C201AC081Q38949296-9150C6BD-4D87-4642-BA76-2AACD8CA7209Q39385222-B5D460BF-DBC9-4C24-B627-F77B64459BF0Q39956430-733FDF37-6461-43D2-B104-8764080C7C1BQ39979226-6FD7BE96-740D-4BF3-9630-F15A4E54B8ACQ40142360-C124A6E9-B8E4-44B1-8A2D-E25DFA6BB182Q40213854-A3307C49-7A90-49C0-BC31-3CF2AD81296CQ40228726-799B5534-CF20-44CC-BAFB-A09B0F2FE368Q40325214-7258C62E-7187-44EA-8BB7-3BC88256C869Q40407383-5604F1EA-CB1A-4FF2-8757-9E813CE6A0B2Q40446389-AA41B8BD-D7B4-4349-BE28-F34014E6D39FQ40455860-FAFF9560-93CA-49C4-BE72-2B11B1980473
P2860
The N-terminal domain of p73 interacts with the CH1 domain of p300/CREB binding protein and mediates transcriptional activation and apoptosis.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
The N-terminal domain of p73 i ...... onal activation and apoptosis.
@en
The N-terminal domain of p73 i ...... onal activation and apoptosis.
@nl
type
label
The N-terminal domain of p73 i ...... onal activation and apoptosis.
@en
The N-terminal domain of p73 i ...... onal activation and apoptosis.
@nl
prefLabel
The N-terminal domain of p73 i ...... onal activation and apoptosis.
@en
The N-terminal domain of p73 i ...... onal activation and apoptosis.
@nl
P2093
P2860
P1476
The N-terminal domain of p73 i ...... onal activation and apoptosis.
@en
P2093
P2860
P304
P356
10.1128/MCB.20.4.1299-1310.2000
P407
P577
2000-02-01T00:00:00Z