Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines.
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Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cellsKilling tumours by ceramide-induced apoptosis: a critique of available drugsAll-trans retinoic acid down-regulates human albumin gene expression through the induction of C/EBPbeta-LIPRoles of bioactive sphingolipids in cancer biology and therapeuticsDihydroceramides: From Bit Players to Lead ActorsVitamin A, cancer treatment and prevention: the new role of cellular retinol binding proteinsTamoxifen regulation of sphingolipid metabolism--Therapeutic implicationsCeramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemiaDynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemiaModification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells.Fenretinide-induced apoptosis of Huh-7 hepatocellular carcinoma is retinoic acid receptor beta dependent.Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma.Phase I Study of Fenretinide Delivered Intravenously in Patients with Relapsed or Refractory Hematologic Malignancies: A California Cancer Consortium Trial.Induction and intracellular localization of Nur77 dictate fenretinide-induced apoptosis of human liver cancer cells.Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium.A mechanically-induced colon cancer cell population shows increased metastatic potential.Retinoids and ovarian cancer.Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cellsAnti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse modelThe oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-hpr: autophagy or apoptosis?BBC3 mediates fenretinide-induced cell death in neuroblastomaSynergistic activity of fenretinide and the Bcl-2 family protein inhibitor ABT-737 against human neuroblastoma.The CLN9 protein, a regulator of dihydroceramide synthase.N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cellsGlioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway.Effects of low-dose ionizing radiation and menadione, an inducer of oxidative stress, alone and in combination in a vertebrate embryo modelThe bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replicationC22:0- and C24:0-dihydroceramides confer mixed cytotoxicity in T-cell acute lymphoblastic leukemia cell lines.Fenretinide corrects the imbalance between omega-6 to omega-3 polyunsaturated fatty acids and inhibits macrophage inflammatory mediators via the ERK pathway.Expression of Pseudomonas aeruginosa toxin ExoS effectively induces apoptosis in host cells.Phase II study of oral capsular 4-hydroxyphenylretinamide (4-HPR/fenretinide) in pediatric patients with refractory or recurrent neuroblastoma: a report from the Children's Oncology GroupCharacterization of the potent neuroprotective properties of the natural vitamin E alpha-tocotrienol.Apoptosis as a novel target for cancer chemoprevention.Recent advances in the immunobiology of ceramide.Molecular profiling of childhood cancer: Biomarkers and novel therapiesFenretinide inhibited de novo ceramide synthesis and proinflammatory cytokines induced by Aggregatibacter actinomycetemcomitans.CXCR4-tropic, but not CCR5-tropic, human immunodeficiency virus infection is inhibited by the lipid raft-associated factors, acyclic retinoid analogs, and cholera toxin B subunit.Flow Cytometric Analysis of 4-HPR-induced Apoptosis and Cell Cycle Arrest in Acute Myelocytic Leukemia Cell Line (NB-4).Bryostatin-1, Fenretinide and 1α,25 (OH)(2)D(3) Induce Growth Inhibition, Apoptosis and Differentiation in T and B Cell-Derived Acute Lymphoblastic Leukemia Cell Lines (CCRF-CEM and Nalm-6)
P2860
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P2860
Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Increase of ceramide and induction of mixed apoptosis/necrosis by N-
@nl
Increase of ceramide and induc ...... e in neuroblastoma cell lines.
@en
type
label
Increase of ceramide and induction of mixed apoptosis/necrosis by N-
@nl
Increase of ceramide and induc ...... e in neuroblastoma cell lines.
@en
prefLabel
Increase of ceramide and induction of mixed apoptosis/necrosis by N-
@nl
Increase of ceramide and induc ...... e in neuroblastoma cell lines.
@en
P2093
P2860
P356
P1476
Increase of ceramide and induc ...... e in neuroblastoma cell lines.
@en
P2093
B J Maurer
C P Reynolds
L S Metelitsa
R C Seeger
P2860
P304
P356
10.1093/JNCI/91.13.1138
P407
P577
1999-07-01T00:00:00Z