Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation.
about
Mechanism for down-regulation of CD28 by Nef.Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I traffickingRabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membraneImmunomodulatory properties of HLA-G in infectious diseasesDesign and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity.The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradationSmall molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef actionNef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP.HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasisNef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabetaThe MHC class I antigen presentation pathway: strategies for viral immune evasion.Proline 78 is crucial for human immunodeficiency virus type 1 Nef to down-regulate class I human leukocyte antigen.The T-cell response to HIV.Nef-mediated disruption of HLA-A2 transport to the cell surface in T cellsConvergence of non-clathrin- and clathrin-derived endosomes involves Arf6 inactivation and changes in phosphoinositides.HIV Nef-mediated major histocompatibility complex class I down-modulation is independent of Arf6 activity.Cooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis.Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef.HIV and SIV CTL escape: implications for vaccine design.HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.Viral modulation of NK cell immunity.Cryptic protein-protein interaction motifs in the cytoplasmic domain of MHCI proteins.Portable flanking sequences modulate CTL epitope processing.HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail.Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunitHuman immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways.HIV-1 Nef: at the crossroadsRetroviral proteomics and interactomes: intricate balances of cell survival and viral replication.Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunityHuman N-myristoyltransferases form stable complexes with lentiviral nef and other viral and cellular substrate proteins.Human natural killer cell receptor functions and their implication in diseases.HIV immune evasion disruption of antigen presentation by the HIV Nef protein.The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins.Targeting HIV latency: resting memory T cells, hematopoietic progenitor cells and future directions.HIV-1 Nef: Taking Control of Protein Trafficking.Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins.A novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages.Transcription of preintegrated HIV-1 cDNA modulates cell surface expression of major histocompatibility complex class I via Nef.
P2860
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P2860
Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Distinct trafficking pathways ...... mplex class I down-regulation.
@en
Distinct trafficking pathways ...... mplex class I down-regulation.
@nl
type
label
Distinct trafficking pathways ...... mplex class I down-regulation.
@en
Distinct trafficking pathways ...... mplex class I down-regulation.
@nl
prefLabel
Distinct trafficking pathways ...... mplex class I down-regulation.
@en
Distinct trafficking pathways ...... mplex class I down-regulation.
@nl
P2093
P2860
P1433
P1476
Distinct trafficking pathways ...... omplex class I down-regulation
@en
P2093
P2860
P304
P356
10.1128/JVI.74.19.9256-9266.2000
P407
P577
2000-10-01T00:00:00Z