A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription.
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Structures of YAP protein domains reveal promising targets for development of new cancer drugsRegulation of TAZ in cancerA Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue SarcomasThe two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatmentYAP and TAZ: a nexus for Hippo signaling and beyondHippo Pathway in Organ Size Control, Tissue Homeostasis, and CancerValidation of chemical compound library screening for transcriptional co-activator with PDZ-binding motif inhibitors using GFP-fused transcriptional co-activator with PDZ-binding motifMolecular Pathways: Hippo Signaling, a Critical Tumor Suppressor.The Hippo signaling pathway and translational opportunities for brain cancersThe role of the Hippo pathway in human disease and tumorigenesisYAP determines the cell fate of injured mouse hepatocytes in vivo.The Hippo pathway in disease and therapy: cancer and beyondDownstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinomaExpression of RASSF6 in kidney and the implication of RASSF6 and the Hippo pathway in the sorbitol-induced apoptosis in renal proximal tubular epithelial cells.Inhibitory effects of dobutamine on human gastric adenocarcinomaDisease implications of the Hippo/YAP pathway.Hippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.The mevalonate pathway regulates primitive streak formation via protein farnesylationNeuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration.Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade.Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells.Cysteine S-Glutathionylation Promotes Stability and Activation of the Hippo Downstream Effector Transcriptional Co-activator with PDZ-binding Motif (TAZ).Antitumor activity of dobutamine on human osteosarcoma cells.The hippo-yes association protein pathway in liver cancerNotch3 inhibits epithelial-mesenchymal transition by activating Kibra-mediated Hippo/YAP signaling in breast cancer epithelial cells.Regulation of the Hippo pathway and implications for anticancer drug development.Antitumor activity of curcumin is involved in down-regulation of YAP/TAZ expression in pancreatic cancer cellsScreening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model.The Hippo signaling pathway provides novel anti-cancer drug targets.The Hippo pathway: regulators and regulations.Okadaic Acid: a tool to study the hippo pathwayThe dual functions of YAP-1 to promote and inhibit cell growth in human malignancy.Hippo-YAP signaling pathway: A new paradigm for cancer therapy.The Hippo signal transduction network in skeletal and cardiac muscle.The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.G protein-coupled receptors: bridging the gap from the extracellular signals to the Hippo pathway.The Hippo transducers TAZ and YAP in breast cancer: oncogenic activities and clinical implications.LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of YapLoss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer
P2860
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P2860
A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
A cell-based assay to screen s ...... -dependent gene transcription.
@en
A cell-based assay to screen s ...... -dependent gene transcription.
@nl
type
label
A cell-based assay to screen s ...... -dependent gene transcription.
@en
A cell-based assay to screen s ...... -dependent gene transcription.
@nl
prefLabel
A cell-based assay to screen s ...... -dependent gene transcription.
@en
A cell-based assay to screen s ...... -dependent gene transcription.
@nl
P2093
P2860
P356
P1476
A cell-based assay to screen s ...... -dependent gene transcription.
@en
P2093
Hiroshi Nishina
Kanchanamala Withanage
Kentaro Nakagawa
Mari Ishigami-Yuasa
Mitsunobu Ikeda
Shoji Hata
Yukiko Okuno
Yutaka Hata
P2860
P304
P356
10.1093/JB/MVR063
P577
2011-05-17T00:00:00Z