Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
about
Suppression of nonhomologous end joining repair by overexpression of HMGA2Differential activation of DNA-PK based on DNA strand orientation and sequence biasInhibition of double-strand break non-homologous end-joining by cisplatin adducts in human cell extractsATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosisKinetic analysis of the Ku-DNA binding activity reveals a redox-dependent alteration in protein structure that stimulates dissociation of the Ku-DNA complexMolecular analysis of Ku redox regulation.A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts.Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs)DNA damage response and repair: insights into strategies for radiation sensitization of gliomasComplex cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathwaysCisplatin sensitizes cancer cells to ionizing radiation via inhibition of nonhomologous end joining.A mechanism for DNA-PK activation requiring unique contributions from each strand of a DNA terminus and implications for microhomology-mediated nonhomologous DNA end joining.DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer.Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA.Synergistic effect of cisplatin and synchrotron irradiation on F98 gliomas growing in nude mice.Sensitizing thermochemotherapy with a PARP1-inhibitor.Coordination of DNA-PK activation and nuclease processing of DNA termini in NHEJ.DNA-dependent protein kinase catalytic subunit. Structural requirements for kinase activation by DNA ends.Role of intercalation and redox potential in DNA photosensitization by ruthenium(II) polypyridyl complexes: assessment using DNA repair protein tests.Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule.DNA-dependent conformational changes in the Ku heterodimer.Analysis of enhancement at small and large radiation doses for effectiveness of inactivation in cultured cells by combining two agents with radiation.A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis.DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination.Specific molecular and cellular events induced by irradiated X-ray photoactivatable drugs raise the problem of co-toxicities: particular consequences for anti-cancer synchrotron therapy.
P2860
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P2860
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
@zh-hk
2000年論文
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2000年論文
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2000年论文
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2000年论文
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2000年论文
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name
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
@en
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
@nl
type
label
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
@en
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
@nl
prefLabel
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
@en
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
@nl
P2093
P2860
P356
P1476
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.
@en
P2093
P2860
P304
P356
10.1093/NAR/28.23.4634
P407
P577
2000-12-01T00:00:00Z