Novel cross-talk within the IKK family controls innate immunity. - Wikidata - wikimedia - TriplyDB

Novel cross-talk within the IKK family controls innate immunity.

Novel cross-talk within the IKK family controls innate immunity.

http://www.wikidata.org/entity/Q39622962

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MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages The TLR and IL-1 signalling network at a glance Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis.Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation At the interface of antioxidant signalling and cellular function: Key polyphenol effects TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling The protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs)Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy.Differential Antagonism of Human Innate Immune Responses by Tick-Borne Phlebovirus Nonstructural Proteins.Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis.IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex.Porcine epidemic diarrhea virus nucleocapsid protein antagonizes beta interferon production by sequestering the interaction between IRF3 and TBK1.STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses.Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase.Mechanism of endogenous regulation of the type I interferon response by suppressor of IκB kinase epsilon (SIKE), a novel substrate of TANK-binding kinase 1 (TBK1).Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells.Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks.A systematic analysis of the peripheral and CNS effects of systemic LPS, IL-1β, [corrected] TNF-α and IL-6 challenges in C57BL/6 mice IKKα negatively regulates ASC-dependent inflammasome activation.Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling.Inhibitors of the interferon response enhance virus replication in vitro.Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance Gene network inference and visualization tools for biologists: application to new human transcriptome datasets.Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400 Molecular characterization, expression of chicken TBK1 gene and its effect on IRF3 signaling pathway

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P2860

Novel cross-talk within the IKK family controls innate immunity.

http://www.wikidata.org/entity/Q39622962

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Novel cross-talk within the IKK family controls innate immunity.

@en

Novel cross-talk within the IKK family controls innate immunity.

@nl

type

label

Novel cross-talk within the IKK family controls innate immunity.

@en

Novel cross-talk within the IKK family controls innate immunity.

@nl

prefLabel

Novel cross-talk within the IKK family controls innate immunity.

@en

Novel cross-talk within the IKK family controls innate immunity.

@nl

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Biochemical Journal

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Novel cross-talk within the IKK family controls innate immunity.

@en

P2093

Edward G McIver

http://www.w3.org/2001/XMLSchema#string

Erick R R Young

http://www.w3.org/2001/XMLSchema#string

Jeffrey B Madwed

http://www.w3.org/2001/XMLSchema#string

Joanne Hough

http://www.w3.org/2001/XMLSchema#string

Kristopher Clark

http://www.w3.org/2001/XMLSchema#string

Lorna Plater

http://www.w3.org/2001/XMLSchema#string

Mark Peggie

http://www.w3.org/2001/XMLSchema#string

Philip Cohen

http://www.w3.org/2001/XMLSchema#string

Ronald J Sorcek

http://www.w3.org/2001/XMLSchema#string

P2860

TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

A ubiquitin ligase complex assembles linear polyubiquitin chains

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

Direct activation of protein kinases by unanchored polyubiquitin chains

High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

The selectivity of protein kinase inhibitors: a further update

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93-104

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scholarly article

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10.1042/BJ20101701

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1

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434

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2011-02-01T00:00:00Z

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49664758

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21138416

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