IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400
about
Tumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancerMAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomasIκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinasesTNF and MAP kinase signalling pathways.TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling.Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis.Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cellsRegulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.c-Jun Is Required for Nuclear Factor-κB-Dependent, LPS-Stimulated Fos-Related Antigen-1 Transcription in Alveolar Macrophages.A preliminary study on methylphenidate-regulated gene expression in lymphoblastoid cells of ADHD patients.Tumor progression locus 2-dependent oxidative burst drives phosphorylation of extracellular signal-regulated kinase during TLR3 and 9 signaling.The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold.The interplay between cyclic AMP, MAPK, and NF-κB pathways in response to proinflammatory signals in microglia.Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate.IKBKB phosphorylates TPL2 (MAP3K8) at Ser4003xUb;p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity.Linear ubiquitin chains: NF-κB signalling, cell death and beyond.
P2860
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P2860
IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
IκB kinase 2 regulates TPL-2 a ...... horylation of TPL-2 serine 400
@ast
IκB kinase 2 regulates TPL-2 a ...... horylation of TPL-2 serine 400
@en
type
label
IκB kinase 2 regulates TPL-2 a ...... horylation of TPL-2 serine 400
@ast
IκB kinase 2 regulates TPL-2 a ...... horylation of TPL-2 serine 400
@en
prefLabel
IκB kinase 2 regulates TPL-2 a ...... horylation of TPL-2 serine 400
@ast
IκB kinase 2 regulates TPL-2 a ...... horylation of TPL-2 serine 400
@en
P2093
P2860
P356
P1476
IκB kinase 2 regulates TPL-2 a ...... horylation of TPL-2 serine 400
@en
P2093
Abduelhakem Ben-Addi
Agnes Mambole-Dema
Huei-Ting Yang
Julia Janzen
Karine Roget
Nick Morrice
Steven C Ley
Thorsten Gantke
P2860
P304
P356
10.1128/MCB.01065-12
P407
P577
2012-09-17T00:00:00Z