Prion protein complexed to N2a cellular RNAs through its N-terminal domain forms aggregates and is toxic to murine neuroblastoma cells
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Intraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian PrionStructure of the Flexible Amino-Terminal Domain of Prion Protein Bound to a Sulfated GlycanShaking alone induces de novo conversion of recombinant prion proteins to β-sheet rich oligomers and fibrilsRole of polysaccharide and lipid in lipopolysaccharide induced prion protein conversionMisfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.Heparin binding confers prion stability and impairs its aggregation.Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins.The role of cofactors in prion propagation and infectivityPropagation of RML prions in mice expressing PrP devoid of GPI anchor leads to formation of a novel, stable prion strainComparison of 2 synthetically generated recombinant prions.Lipopolysaccharide induced conversion of recombinant prion protein.Sequestration of cellular interacting partners by protein aggregates: implication in a loss-of-function pathology.Nucleic acid induced unfolding of recombinant prion protein globular fragment is pH dependent.Inhibition of TDP-43 aggregation by nucleic acid bindingCyclin-dependent kinase 5 phosphorylation of familial prion protein mutants exacerbates conversion into amyloid structure.Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity.Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation.Anti-bovine prion protein RNA aptamer containing tandem GGA repeat interacts both with recombinant bovine prion protein and its beta isoform with high affinityPrion protein-coated magnetic beads: synthesis, characterization and development of a new ligands screening method.De novo generation of infectious prions with bacterially expressed recombinant prion protein.The peculiar interaction between mammalian prion protein and RNAAllosteric function and dysfunction of the prion protein.The role of RNA in mammalian prion protein conversion.Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids.Analysis of nucleic acid chaperoning by the prion protein and its inhibition by oligonucleotides.Embryonic lethal abnormal vision proteins and adenine and uridine-rich element mRNAs after global cerebral ischemia and reperfusion in the rat.Melanin or a Melanin-Like Substance Interacts with the N-Terminal Portion of Prion Protein and Inhibits Abnormal Prion Protein Formation in Prion-Infected Cells.The "Jekyll and Hyde" Actions of Nucleic Acids on the Prion-like Aggregation of Proteins.Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?Prion-like proteins and their computational identification in proteomes.Pathological implications of nucleic acid interactions with proteins associated with neurodegenerative diseasesSelf-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity.Sequestration of Ribosome during Protein Aggregate Formation: Contribution of ribosomal RNABiophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids.Cross-talk between the octarepeat domain and the fifth binding site of prion protein driven by the interaction of copper(II) with the N-terminus.A quantitative characterization of interaction between prion protein with nucleic acids.
P2860
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P2860
Prion protein complexed to N2a cellular RNAs through its N-terminal domain forms aggregates and is toxic to murine neuroblastoma cells
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Prion protein complexed to N2a ...... to murine neuroblastoma cells
@en
Prion protein complexed to N2a ...... to murine neuroblastoma cells.
@nl
type
label
Prion protein complexed to N2a ...... to murine neuroblastoma cells
@en
Prion protein complexed to N2a ...... to murine neuroblastoma cells.
@nl
prefLabel
Prion protein complexed to N2a ...... to murine neuroblastoma cells
@en
Prion protein complexed to N2a ...... to murine neuroblastoma cells.
@nl
P2093
P2860
P356
P1476
Prion protein complexed to N2a ...... to murine neuroblastoma cells
@en
P2093
Marcius S Almeida
Mariana P B Gomes
Narcisa L Cunha e Silva
Priscila S Ferreira
Thiago A Millen
Tuane C R G Vieira
P2860
P304
19616-19625
P356
10.1074/JBC.M802102200
P407
P577
2008-05-01T00:00:00Z