Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.
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Evaluation of traditional medicines for neurodegenerative diseases using Drosophila modelsTaxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate siteDevelopment of B cells and erythrocytes is specifically impaired by the drug celastrol in miceNF-kappa B modulation is involved in celastrol induced human multiple myeloma cell apoptosisEffects of Huanglian-Jie-Du-Tang and its modified formula on the modulation of amyloid-β precursor protein processing in Alzheimer's disease modelsThe effect of PN-1, a Traditional Chinese Prescription, on the Learning and Memory in a Transgenic Mouse Model of Alzheimer's Disease.Alzheimer's disease: evidence for the expression of interleukin-33 and its receptor ST2 in the brainThe systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice.Celastrol attenuates inflammatory and neuropathic pain mediated by cannabinoid receptor type 2.Hsp70 and its molecular role in nervous system diseasesTargeting NOX enzymes in the central nervous system: therapeutic opportunities.Heat shock protein 90 in Alzheimer's diseaseThe spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation.Celastrol protects ischaemic myocardium through a heat shock response with up-regulation of haeme oxygenase-1.Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells.Molecular chaperones in Parkinson's disease--present and futureChronic IL-1β-mediated neuroinflammation mitigates amyloid pathology in a mouse model of Alzheimer's disease without inducing overt neurodegenerationMinocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology.Inhibition of inflammation with celastrol fails to improve muscle function in dysferlin-deficient A/J miceBryostatin-1 vs. TPPB: dose-dependent APP processing and PKC-α, -δ, and -ε isoform activation in SH-SY5Y neuronal cells.A novel approach to recovery of function of mutant proteins by slowing down translation.BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's diseaseBACE1 in the retina: a sensitive biomarker for monitoring early pathological changes in Alzheimer's disease.The central role of heat shock factor 1 in synaptic fidelity and memory consolidationThe Aqueous Extract of Rhizome of Gastrodia elata Protected Drosophila and PC12 Cells against Beta-Amyloid-Induced Neurotoxicity.Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model.Knock-down of protein L-isoaspartyl O-methyltransferase increases β-amyloid production by decreasing ADAM10 and ADAM17 levelsProtein Quality Control by Molecular Chaperones in Neurodegeneration.Association of heat-shock proteins in various neurodegenerative disorders: is it a master key to open the therapeutic door?Barcoding heat shock proteins to human diseases: looking beyond the heat shock responseMolecular chaperones and neuronal proteostasis.Inhibition of IKKβ by celastrol and its analogues - an in silico and in vitro approach.Induction of heat shock proteins in differentiated human neuronal cells following co-application of celastrol and arimoclomol.The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained.Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease.Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease.Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations.Localization of heat shock proteins in cerebral cortical cultures following induction by celastrolCelastrol: A Spectrum of Treatment Opportunities in Chronic DiseasesFlavonoids lower Alzheimer's Aβ production via an NFκB dependent mechanism.
P2860
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P2860
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Reduction of beta-amyloid path ...... model of Alzheimer's disease.
@en
Reduction of beta-amyloid path ...... model of Alzheimer's disease.
@nl
type
label
Reduction of beta-amyloid path ...... model of Alzheimer's disease.
@en
Reduction of beta-amyloid path ...... model of Alzheimer's disease.
@nl
prefLabel
Reduction of beta-amyloid path ...... model of Alzheimer's disease.
@en
Reduction of beta-amyloid path ...... model of Alzheimer's disease.
@nl
P2093
P2860
P50
P356
P1476
Reduction of beta-amyloid path ...... model of Alzheimer's disease.
@en
P2093
Amelia March
Corbin Bachmeier
Daniel Paris
David Beaulieu-Abdelahad
Nowell J Ganey
Vincent Laporte
P2860
P2888
P356
10.1186/1742-2094-7-17
P577
2010-03-08T00:00:00Z
P5875
P6179
1026746873