PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein.
about
Protein kinase C signaling and cell cycle regulationMirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblastsExamination of the expanding pathways for the regulation of p21 expression and activity.p21 in cancer: intricate networks and multiple activitiesProtein kinase C delta (PKCδ) affects proliferation of insulin-secreting cells by promoting nuclear extrusion of the cell cycle inhibitor p21Cip1/WAF1.Differential effects of 5-aminolaevulinic acid photodynamic therapy and psoralen + ultraviolet A therapy on p53 phosphorylation in normal human skin in vivo.Cdk2-dependent phosphorylation of p21 regulates the role of Cdk2 in cisplatin cytotoxicityHuman NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activationBinding of Kif23-iso1/CHO1 to 14-3-3 is regulated by sequential phosphorylations at two LATS kinase consensus sitesApicobasal polarity and cell proliferation during development.Less understood issues: p21(Cip1) in mitosis and its therapeutic potential.Post-transcriptional destabilization of p21cip1 by protein kinase C in fibroblasts.Expression of proviral integration site for Moloney murine leukemia virus 1 (Pim-1) is post-transcriptionally regulated by tristetraprolin in cancer cells.Bimodal regulation of p21(waf1) protein as function of DNA damage levels.PKCι depletion initiates mitotic slippage-induced senescence in glioblastomaThe p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.Repression of cancer cell senescence by PKCι.Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells.Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21Cip1.Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.aPKC phosphorylates p27Xic1, providing a mechanistic link between apicobasal polarity and cell-cycle control.MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability.Binding of calmodulin to the carboxy-terminal region of p21 induces nuclear accumulation via inhibition of protein kinase C-mediated phosphorylation of Ser153.PAK4 is required for regulation of the cell-cycle regulatory protein p21, and for control of cell-cycle progression.
P2860
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P2860
PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
PDK1-dependent activation of a ...... e p21 tumour modifier protein.
@en
PDK1-dependent activation of a ...... e p21 tumour modifier protein.
@nl
type
label
PDK1-dependent activation of a ...... e p21 tumour modifier protein.
@en
PDK1-dependent activation of a ...... e p21 tumour modifier protein.
@nl
prefLabel
PDK1-dependent activation of a ...... e p21 tumour modifier protein.
@en
PDK1-dependent activation of a ...... e p21 tumour modifier protein.
@nl
P2860
P356
P1433
P1476
PDK1-dependent activation of a ...... he p21 tumour modifier protein
@en
P2093
Angela Ingram
Kathryn L Ball
P2860
P304
P356
10.1093/EMBOJ/CDF684
P407
P50
P577
2002-12-01T00:00:00Z