Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility.
about
The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.Dynamic functions of RhoA in tumor cell migration and invasionInactivation of Icmt inhibits transformation by oncogenic K-Ras and B-RafHyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasionS1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cellsNet1 and Myeov: computationally identified mediators of gastric cancerRhoE binds to ROCK I and inhibits downstream signalingAstrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegenerationStructural Mechanisms and Drug Discovery Prospects of Rho GTPasesbFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healingSmall-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growthGbetagamma recruits Rho1 to the site of polarized growth during mating in budding yeast.ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migrationAngiostatin effects on endothelial cells mediated by ceramide and RhoA.mDia1 targets v-Src to the cell periphery and facilitates cell transformation, tumorigenesis, and invasionThe role of Dlc1 isoform 2 in K-Ras2(G12D) induced thymic cancerDysregulated serum response factor triggers formation of hepatocellular carcinomaIdentification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoformCaveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesisTreponema denticola major outer sheath protein induces actin assembly at free barbed ends by a PIP2-dependent uncapping mechanism in fibroblastsB-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblastsSuppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinaseAP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondifferentially expressed proteins.Myocardin related transcription factors are required for coordinated cell cycle progression.B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organizationp190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.Oncogenic H-Ras V12 promotes anchorage-independent cytokinesis in human fibroblastsDisruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42.An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments.Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction.Ral is both necessary and sufficient for the inhibition of myeloid differentiation mediated by RasBioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.Quantifying myosin light chain phosphorylation in single adherent cells with automated fluorescence microscopyp27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer.Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding.Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts.ERK-MAPK signaling opposes rho-kinase to reduce cardiomyocyte apoptosis in heart ischemic preconditioning.
P2860
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P2860
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Cross-talk between Ras and Rho ...... ration and increased motility.
@en
Cross-talk between Ras and Rho ...... ration and increased motility.
@nl
type
label
Cross-talk between Ras and Rho ...... ration and increased motility.
@en
Cross-talk between Ras and Rho ...... ration and increased motility.
@nl
prefLabel
Cross-talk between Ras and Rho ...... ration and increased motility.
@en
Cross-talk between Ras and Rho ...... ration and increased motility.
@nl
P2860
P356
P1433
P1476
Cross-talk between Ras and Rho ...... ration and increased motility.
@en
P2093
C J Marshall
P2860
P304
P356
10.1093/EMBOJ/20.4.755
P407
P577
2001-02-01T00:00:00Z