Protein dynamics in drug combinations: a linear superposition of individual-drug responses.
about
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewMultiscale models of cell signaling.Status of PI3K/Akt/mTOR pathway inhibitors in lymphomaDynamic proteomics of human protein level and localization across the cell cycleEpigenetic polypharmacology: from combination therapy to multitargeted drugsEfficient discovery of anti-inflammatory small-molecule combinations using evolutionary computingCDA: combinatorial drug discovery using transcriptional response modulesPerturbation biology: inferring signaling networks in cellular systemsDiscovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergiesQuantification of Interactions between Dynamic Cellular Network Functionalities by Cascaded LayeringChemogenomics and orthology-based design of antibiotic combination therapiesTNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors.Models of signalling networks - what cell biologists can gain from them and give to themPairwise network mechanisms in the host signaling response to coxsackievirus B3 infection.Measuring mRNA copy number in individual Escherichia coli cells using single-molecule fluorescent in situ hybridization.ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments.Modeling the zebrafish segmentation clock's gene regulatory network constrained by expression data suggests evolutionary transitions between oscillating and nonoscillating transcriptionResolution of gene regulatory conflicts caused by combinations of antibiotics.Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazoleTime-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation.Metabolomic high-content nuclear magnetic resonance-based drug screening of a kinase inhibitor libraryExploring drug combinations in genetic interaction networkMultiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators.Encoding and decoding cellular information through signaling dynamics.The drug cocktail networkDrug discovery: engineering drug combinationsGeneral properties of transcriptional time series in Escherichia coli.Linear superposition and prediction of bacterial promoter activity dynamics in complex conditions.A streamlined search technology for identification of synergistic drug combinations.Mechanism-independent method for predicting response to multidrug combinations in bacteria.Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis.Dynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitorDefining principles of combination drug mechanisms of actionA dynamic plasma membrane proteome analysis of alcohol-induced liver cirrhosis.Systems Biology of Immunomodulation for Post-Stroke Neuroplasticity: Multimodal Implications of Pharmacotherapy and NeurorehabilitationGlobal cellular response to chemotherapy-induced apoptosis.Pairwise interactions and the battle against combinatorics in multidrug therapies.High-throughput, single-cell NF-κB dynamics.Network-based drug repositioning.Bacterial responses to antibiotics and their combinations.
P2860
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P2860
Protein dynamics in drug combinations: a linear superposition of individual-drug responses.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Protein dynamics in drug combi ...... of individual-drug responses.
@en
Protein dynamics in drug combi ...... of individual-drug responses.
@nl
type
label
Protein dynamics in drug combi ...... of individual-drug responses.
@en
Protein dynamics in drug combi ...... of individual-drug responses.
@nl
prefLabel
Protein dynamics in drug combi ...... of individual-drug responses.
@en
Protein dynamics in drug combi ...... of individual-drug responses.
@nl
P2093
P1433
P1476
Protein dynamics in drug combi ...... of individual-drug responses.
@en
P2093
Ariel A Cohen
Erez Dekel
Lydia Cohen
Naama Geva-Zatorsky
Tamar Danon
P304
P356
10.1016/J.CELL.2010.02.011
P407
P577
2010-03-01T00:00:00Z