Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model.
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Dysfunctional ryanodine receptors in the heart: new insights into complex cardiovascular diseasesReview of novel therapeutic targets for improving heart failure treatment based on experimental and clinical studies'Ryanopathy': causes and manifestations of RyR2 dysfunction in heart failureCardiac ryanodine receptors control heart rate and rhythmicity in adult miceA new rodent model for obstructive sleep apnea: effects on ATP-mediated dilations in cerebral arteriesLoss of MD1 exacerbates pressure overload-induced left ventricular structural and electrical remodelling.Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice.Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in miceRyanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failureThree 4-letter words of hypertension-related cardiac hypertrophy: TRPC, mTOR, and HDAC.Targeting cardiomyocyte Ca2+ homeostasis in heart failure.The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the HeartUp-regulation of sarcoplasmic reticulum Ca(2+) uptake leads to cardiac hypertrophy, contractile dysfunction and early mortality in mice deficient in CASQ2.Atrial identity is determined by a COUP-TFII regulatory network.Novel junctophilin-2 mutation A405S is associated with basal septal hypertrophy and diastolic dysfunction.Ryanodine receptor phosphorylation, calcium/calmodulin-dependent protein kinase II, and life-threatening ventricular arrhythmias.Emerging roles of junctophilin-2 in the heart and implications for cardiac diseases.Transverse aortic constriction in mice.RyR2 QQ2958 Genotype and Risk of Malignant Ventricular ArrhythmiasDecreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice.Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release.Function of the CaMKII-ryanodine receptor signaling pathway in rabbits with left ventricular hypertrophy and triggered ventricular arrhythmia.A leakage leads to failure: roles of sarcoplasmic reticulum Ca2+ leak via RyR2 in heart failure progression.R4496C RyR2 mutation impairs atrial and ventricular contractility.Diverse regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes.Identification of novel genes significantly affecting growth in catfish through GWAS analysis.Sirtuin 5 is required for mouse survival in response to cardiac pressure overload.Effect of distinct sources of Ca(2+) on cardiac hypertrophy in cardiomyocytes.Nitric Oxide-cGMP-PKG Pathway Acts on Orai1 to Inhibit the Hypertrophy of Human Embryonic Stem Cell-Derived Cardiomyocytes.Cardiac FKBP12.6 overexpression protects against triggered ventricular tachycardia in pressure overloaded mouse hearts.
P2860
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P2860
Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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name
Accelerated development of pre ...... yR2-R176Q knockin mouse model.
@en
Accelerated development of pre ...... yR2-R176Q knockin mouse model.
@nl
type
label
Accelerated development of pre ...... yR2-R176Q knockin mouse model.
@en
Accelerated development of pre ...... yR2-R176Q knockin mouse model.
@nl
prefLabel
Accelerated development of pre ...... yR2-R176Q knockin mouse model.
@en
Accelerated development of pre ...... yR2-R176Q knockin mouse model.
@nl
P2093
P2860
P1433
P1476
Accelerated development of pre ...... yR2-R176Q knockin mouse model.
@en
P2093
Angela C De Almeida
Corey Reynolds
Darlene G Skapura
Jonathan L Respress
Leon J De Windt
Ralph J van Oort
P2860
P304
P356
10.1161/HYPERTENSIONAHA.109.146449
P407
P577
2010-02-15T00:00:00Z