Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.
about
Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetesT cell epitopes and post-translationally modified epitopes in type 1 diabetesImmune therapy in type 1 diabetes mellitusIdentification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).Peptide-MHC cellular microarray with innovative data analysis system for simultaneously detecting multiple CD4 T-cell responsesIdentification of HLA class II-restricted determinants of Mycobacterium tuberculosis-derived proteins by using HLA-transgenic, class II-deficient mice.Genetic susceptibility factors of Type 1 diabetes in Asians.T-cell tolerance and autoimmune diabetes.Transgenic models of autoimmune disease.Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes.Macronutrient deprivation modulates antigen trafficking and immune recognition through HSC70 accessibility.Sidechain biology and the immunogenicity of PDC-E2, the major autoantigen of primary biliary cirrhosis.Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice.Antigen-specific CD4+ T cells recognize epitopes of protective antigen following vaccination with an anthrax vaccine.The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic modelIdentification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells.Cytoplasmic processing is a prerequisite for presentation of an endogenous antigen by major histocompatibility complex class II proteins.Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice.Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein.Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.HSP90alpha and HSP90beta isoforms selectively modulate MHC class II antigen presentation in B cells.Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice.A humanized mouse model of autoimmune insulitis.T cell recognition of autoantigens in human type 1 diabetes: clinical perspectivesThe targeting of β-cells by T lymphocytes in human type 1 diabetes: clinical perspectives.Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and AutoimmunityRecognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.LAMP-2-deficient human B cells exhibit altered MHC class II presentation of exogenous antigens.Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients.HLA transgenic mice as humanized mouse models of disease and immunity.Low-affinity major histocompatibility complex-binding peptides in type 1 diabetes.Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient.Selecting culprits in type 1 diabetes beta-cell killing.T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes.Molecular mimicry and the pathogenesis of insulin-dependent diabetes mellitus: still just an attractive hypothesis.Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65.Regulatory T cell-associated activity in photopheresis-induced immune tolerance in recent onset type 1 diabetes children.Review of the potential health impact of β-casomorphins and related peptides
P2860
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P2860
Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Naturally processed T cell epi ...... HC class II allele, DRB1*0401.
@en
Naturally processed T cell epi ...... HC class II allele, DRB1*0401.
@nl
type
label
Naturally processed T cell epi ...... HC class II allele, DRB1*0401.
@en
Naturally processed T cell epi ...... HC class II allele, DRB1*0401.
@nl
prefLabel
Naturally processed T cell epi ...... HC class II allele, DRB1*0401.
@en
Naturally processed T cell epi ...... HC class II allele, DRB1*0401.
@nl
P2093
P2860
P356
P1476
Naturally processed T cell epi ...... HC class II allele, DRB1*0401.
@en
P2093
Cummings R
Elliott JF
Lernmark A
Peterson LB
Rothbard JB
P2860
P304
P356
10.1172/JCI119079
P407
P577
1996-12-01T00:00:00Z