Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
about
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticalsBroad targeting of angiogenesis for cancer prevention and therapyCelastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells.ER stress-mediated apoptosis induced by celastrol in cancer cells and important role of glycogen synthase kinase-3β in the signal network.Celastrol stimulates hypoxia-inducible factor-1 activity in tumor cells by initiating the ROS/Akt/p70S6K signaling pathway and enhancing hypoxia-inducible factor-1α protein synthesis.Celastrol regulates multiple nuclear transcription factors belonging to HSP90's clients in a dose- and cell type-dependent way.Shikonin kills glioma cells through necroptosis mediated by RIP-1Peptide deformylase inhibitor actinonin reduces celastrol's HSP70 induction while synergizing proliferation inhibition in tumor cellsCelastrol Ameliorates Ulcerative Colitis-Related Colorectal Cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition.The ubiquitin-proteasome system in glioma cell cycle control.Mechanisms of proteasome inhibitor-induced cytotoxicity in malignant glioma.Cytotoxic effect of celastrol alone or in combination with paclitaxel on anaplastic thyroid carcinoma cells.ATF2 contributes to cisplatin resistance in non-small cell lung cancer and celastrol induces cisplatin resensitization through inhibition of JNK/ATF2 pathway.Celastrol induces unfolded protein response-dependent cell death in head and neck cancer.Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells.Increased 8-hydroxydeoxyguanosine in high-grade gliomas is associated with activation of autophagy.Antitumor activity of tripterine via cell-penetrating peptide-coated nanostructured lipid carriers in a prostate cancer model.Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells.The proteasome inhibitor lactacystin exerts its therapeutic effects on glioma via apoptosis: an in vitro and in vivo study.New strategy of photodynamic treatment of TiO2 nanofibers combined with celastrol for HepG2 proliferation in vitro.Celastrol induces mitochondria-mediated apoptosis in hepatocellular carcinoma Bel-7402 cells.
P2860
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P2860
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
@en
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
@nl
type
label
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
@en
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
@nl
prefLabel
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
@en
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
@nl
P2093
P2860
P1476
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
@en
P2093
Fankai Meng
Pengfei Ge
Shuangliin Fu
Xiaofei Wang
Xunming Ji
Yuchuan Ding
P2860
P304
P356
10.1179/016164109X12518779082273
P577
2009-11-11T00:00:00Z