Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation.
about
Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Galphai proteins and matrix metalloproteinase-9.Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo.Unlike for human monocytes after LPS activation, release of TNF-α by THP-1 cells is produced by a TACE catalytically different from constitutive TACE.Effect of thymoquinone on cytosolic pH and Na+/H+ exchanger activity in mouse dendritic cells.Contrasting actions of diesel exhaust particles on the pulmonary and cardiovascular systems and the effects of thymoquinone.Spleen tyrosine kinase (Syk)-dependent calcium signals mediate efficient CpG-induced exocytosis of tumor necrosis factor α (TNFα) in innate immune cells.Effects of Nigella sativa oil extract on inflammatory cytokine response and oxidative stress status in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial.From here to eternity - the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond.Transcriptional control of the TNF geneNatural and synthetic α,β-unsaturated carbonyls for NF-κB inhibition.The generation, detection, and effects of reactive drug metabolites.Monoterpenes with analgesic activity--a systematic review.DYRK1A phoshorylates histone H3 to differentially regulate the binding of HP1 isoforms and antagonize HP1-mediated transcriptional repression.The Antioxidant Effects of Thymoquinone in Activated BV-2 Murine Microglial Cells.Panacea seed "Nigella": A review focusing on regenerative effects for gastric ailments.Chemopreventive and therapeutic potentials of thymoquinone in HepG2 cells: mechanistic perspectives.Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa.Thymoquinone as a Potential Adjuvant Therapy for Cancer Treatment: Evidence from Preclinical Studies.Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.The effect of thymoquinone on the renal functions following ischemia-reperfusion injury in the rat.Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin.Anti-Inflammatory Activity Is a Possible Mechanism by Which the Polyherbal Formulation Comprised of Nigella sativa (Seeds), Hemidesmus indicus (Root), and Smilax glabra (Rhizome) Mediates Its Antihepatocarcinogenic EffectsThymoquinone attenuates cyclophosphamide-induced pulmonary injury in rats.Thymoquinone decreases AGE-induced NF-kappaB activation in proximal tubular epithelial cells.Thymoquinone ameliorates renal oxidative damage and proliferative response induced by mercuric chloride in rats.Thymoquinone protects renal tubular cells against tubular injury.Presenting a New Standard Drug Model for Turmeric and Its Prized Extract, Curcumin.Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines and the gene expression NFκB pathway signaling targets in LPS/IFNγ -activated BV-2 microglia cells.Nigella sativa as an anti-inflammatory agent in asthma
P2860
Q33538715-FB0D854A-5A5F-4436-A912-6A2EBB2F8385Q33653348-1E70C445-D8DC-48A2-BC75-033A6644E24BQ34222217-57A404C5-DBA5-49DD-8714-FA72D3AA25E6Q34261109-87D083E7-ABFB-47BD-AC86-56985766F450Q35636120-AF306349-53D5-49D4-9FB5-DE470F3E0B25Q36812302-94099BB4-EB6B-4ACC-A033-41FE247FAA9FQ36944947-10BD8FDF-34F3-4D3E-AF12-0E28C2B5E90CQ36974036-B2C77C49-9517-430F-8C78-C7F931A9FB57Q37696067-F9C1C8A1-9A2C-44C0-A311-8926933C1AF4Q37855873-819BA909-D7A2-4D6C-ABD8-90B8FF8025BEQ38054629-02F76F90-87E6-43E0-A1F5-18B43D301E5BQ38072362-AFC7F87A-143A-4EA2-94D0-4D8C047B6C1CQ38307139-0E4C2C53-A429-4101-A711-4CCD19970098Q38748655-85B0D881-BEFE-4A97-AB22-00E6C07A3A40Q38864505-AB6F1C80-3C61-4648-9E6E-88F6AD95A29EQ38896732-AE85F322-A167-46A5-BDD6-3D9EE257CD2CQ39111541-3BED1888-BB11-465B-BEB7-7ADB6C3CDA9FQ39403430-3FA6C2E2-C946-4E68-AF72-B1DCC7CCBF8DQ39780536-290071CF-ED41-4E13-87E0-C1EAD76AC784Q40632506-A1802130-0BAC-41C1-BBED-5D09BF37BC63Q42363810-3DDA39C3-4465-471B-BEE4-C41BE4B925DEQ42397962-F725C30A-2C1E-4F67-ACBF-280C5530ACB2Q44146637-18A7D1F9-32B3-4D4E-8D28-0FD58C320931Q46150813-DA3726C3-FD0F-426C-ABC0-0A0D9431DAA2Q46347824-8985AAFA-37DF-42EE-B649-6C5B8926095FQ46797794-641BA878-E714-416D-9DC2-50FB464BF13EQ52641505-A4C551D5-0613-46DF-9575-54F4697F880DQ55686847-912875FE-0B74-404B-BC85-3A7DF80D4DA0Q57809557-66D0AE65-5EA3-4265-A606-F637B5284977
P2860
Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Thymoquinone attenuates proinf ...... appaB nuclear transactivation.
@en
type
label
Thymoquinone attenuates proinf ...... appaB nuclear transactivation.
@en
prefLabel
Thymoquinone attenuates proinf ...... appaB nuclear transactivation.
@en
P2093
P1476
Thymoquinone attenuates proinf ...... appaB nuclear transactivation.
@en
P2093
Mark R Nicolls
Mohamed A El Gazzar
Rabab El Mezayen
Stephen C Dreskin
P304
P356
10.1016/J.BBAGEN.2007.01.002
P577
2007-01-12T00:00:00Z