Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin.
about
A functional framework for interpretation of genetic associations in T1DPositive and negative selection of the T cell repertoire: what thymocytes see (and don't see)Investigating the role of T-cell avidity and killing efficacy in relation to type 1 diabetes prediction.Avidity-dependent programming of autoreactive T cells in T1DAutoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis.Prediction and pathogenesis in type 1 diabetes.New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation.MHC class II tetramersAutoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetesYeast one-hybrid screen of a thymus epithelial library identifies ZBTB7A as a regulator of thymic insulin expressionGenetic analysis of adult-onset autoimmune diabetesHistorical overview of immunological tolerance.An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients.Non-antigenic and antigenic interventions in type 1 diabetesObstacles and opportunities for targeting the effector T cell response in type 1 diabetes.Comparative genetics: synergizing human and NOD mouse studies for identifying genetic causation of type 1 diabetesCurrent approaches to measuring human islet-antigen specific T cell function in type 1 diabetes.The potential of multimer technologies in type 1 diabetes prediction strategies.The multiple origins of Type 1 diabetes.Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals.The IL-2/IL-2R system: from basic science to therapeutic applications to enhance immune regulation.Immune modulation in humans: implications for type 1 diabetes mellitus.Molecular mechanisms in autoimmune type 1 diabetes: a critical review.Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.Rapid identification and expression of human TCRs in retrogenic mice.Activation of islet autoreactive naïve T cells in infants is influenced by homeostatic mechanisms and antigen-presenting capacity.The case for an autoimmune aetiology of type 1 diabetes.A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion.Deciphering the Pathogenesis of Human Type 1 Diabetes (T1D) by Interrogating T Cells from the "Scene of the Crime".Association between INS-VNTR polymorphism and polycystic ovary syndrome in a Korean population.Autoreactive T cells in type 1 diabetes.Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex.CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity.HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.
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P2860
Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Insulin gene VNTR genotype ass ...... immune response to proinsulin.
@en
Insulin gene VNTR genotype ass ...... immune response to proinsulin.
@nl
type
label
Insulin gene VNTR genotype ass ...... immune response to proinsulin.
@en
Insulin gene VNTR genotype ass ...... immune response to proinsulin.
@nl
prefLabel
Insulin gene VNTR genotype ass ...... immune response to proinsulin.
@en
Insulin gene VNTR genotype ass ...... immune response to proinsulin.
@nl
P2093
P2860
P356
P1433
P1476
Insulin gene VNTR genotype ass ...... immune response to proinsulin.
@en
P2093
H G Shilling
I Durinovic-Belló
V H Gersuk
P2860
P2888
P304
P356
10.1038/GENE.2009.108
P577
2010-01-07T00:00:00Z
P5875
P6179
1003685036