T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin.
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Heterogeneity of B Cell Functions in Stroke-Related Risk, Prevention, Injury, and RepairT cell epitope mapping of JC polyoma virus-encoded proteome reveals reduced T cell responses in HLA-DRB1*04:01+ donorsDifferential responses to Smith D autoantigen by mice with HLA-DR and HLA-DQ transgenes: dominant responses by HLA-DR3 transgenic mice with diversification of autoantibodies to small nuclear ribonucleoprotein, double-stranded DNA, and nuclear antigePro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes.HLA class II transgenic mice as models of human diseases.HLA class II transgenic mice: models of the human CD4+ T-cell immune response.Genetic susceptibility factors of Type 1 diabetes in Asians.T-cell tolerance and autoimmune diabetes.Transgenic models of autoimmune disease.Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD miceDRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in healthAge-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice.Islet autoantigens: structure, function, localization, and regulation.Identification of a MHC class II-restricted human gp100 epitope using DR4-IE transgenic miceInsulin as an autoantigen in NOD/human diabetesAutoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice.Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.HLA-DRB1*0401 and HLA-DRB1*0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis.Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic miceRegulatory T-cell adoptive immunotherapy: potential for treatment of autoimmunity.T cell recognition of autoantigens in human type 1 diabetes: clinical perspectivesThe targeting of β-cells by T lymphocytes in human type 1 diabetes: clinical perspectives.Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes.Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin.T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis-associated and nonassociated HLA-DR4 alleles.Epitopes of the NS3 protein of hepatitis C virus: recognition in HLA-DR4 transgenic mice.Enterovirus infection may induce humoral immune response reacting with islet cell autoantigens in humans.Coxsackievirus immunization delays onset of diabetes in non-obese diabetic mice.Dendritic cell-based assays, but not mannosylation of antigen, improves detection of T-cell responses to proinsulin in type 1 diabetes.The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.Identification of autoantigen epitopes in MHC class II transgenic mice.
P2860
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P2860
T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
T cell epitopes of insulin def ...... preproinsulin and proinsulin.
@ast
T cell epitopes of insulin def ...... preproinsulin and proinsulin.
@en
type
label
T cell epitopes of insulin def ...... preproinsulin and proinsulin.
@ast
T cell epitopes of insulin def ...... preproinsulin and proinsulin.
@en
prefLabel
T cell epitopes of insulin def ...... preproinsulin and proinsulin.
@ast
T cell epitopes of insulin def ...... preproinsulin and proinsulin.
@en
P2093
P2860
P356
P1476
T cell epitopes of insulin def ...... preproinsulin and proinsulin.
@en
P2093
G Sønderstrup
S De Virgiliis
P2860
P304
P356
10.1073/PNAS.95.7.3833
P407
P50
P577
1998-03-01T00:00:00Z