Recombinant human arginase inhibits the in vitro and in vivo proliferation of human melanoma by inducing cell cycle arrest and apoptosis.
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Arginine deprivation therapy for malignant melanomaArginine Metabolism in Bacterial Pathogenesis and Cancer TherapyAmino acid deprivation using enzymes as a targeted therapy for cancer and viral infectionsGrowth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts.Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivationl-Arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cells.Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target.Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatinActivation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells.Arginine de novo and nitric oxide production in disease states.Recombinant human arginase induced caspase-dependent apoptosis and autophagy in non-Hodgkin's lymphoma cellsA novel and promising therapeutic approach for NSCLC: recombinant human arginase alone or combined with autophagy inhibitor.Myeloid-derived suppressor cells (MDSCs) in gliomas and glioma-development.Development of systemic therapy for hepatocellular carcinoma at 2013: updates and insights.Novel therapeutic targets and predictive markers for hepatocellular carcinoma.Drug-induced amino acid deprivation as strategy for cancer therapy.Optimising the combination dosing strategy of abemaciclib and vemurafenib in BRAF-mutated melanoma xenograft tumours.Blocking autophagy enhanced leukemia cell death induced by recombinant human arginase.Arginine dependence of tumor cells: targeting a chink in cancer's armor.Three-dimensional environment renders cancer cells profoundly less susceptible to a single amino acid starvation.Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells.Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity.Preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and quality of life study of pegylated recombinant human arginase 1 in patients with advanced hepatocellular carcinoma.Nanobiotechnological Nanocapsules Containing Polyhemoglobin-Tyrosinase: Effects on Murine B16F10 Melanoma Cell Proliferation and AttachmentDeprivation of arginine by recombinant human arginase in prostate cancer cells.Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma.Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer
P2860
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P2860
Recombinant human arginase inhibits the in vitro and in vivo proliferation of human melanoma by inducing cell cycle arrest and apoptosis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Recombinant human arginase inh ...... ll cycle arrest and apoptosis.
@en
Recombinant human arginase inh ...... ll cycle arrest and apoptosis.
@nl
type
label
Recombinant human arginase inh ...... ll cycle arrest and apoptosis.
@en
Recombinant human arginase inh ...... ll cycle arrest and apoptosis.
@nl
prefLabel
Recombinant human arginase inh ...... ll cycle arrest and apoptosis.
@en
Recombinant human arginase inh ...... ll cycle arrest and apoptosis.
@nl
P2093
P2860
P1476
Recombinant human arginase inh ...... ell cycle arrest and apoptosis
@en
P2093
Denys N Wheatley
Gabriel K Y Wong
Hiu-Chi Chong
Ho-Yin Chow
Paul N M Cheng
Sui-Yi Kwok
Tsz-Lung Chow
Wai-Hung Lo
P2860
P304
P356
10.1111/J.1755-148X.2010.00798.X
P577
2010-12-06T00:00:00Z