North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.

about

Synthesis of conformationally North-locked pyrimidine nucleosides built on an oxabicyclo[3.1.0]hexane scaffold.The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase.

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P2860

North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.

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http://www.wikidata.org/entity/Q39836948

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2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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name

North- and south-bicyclo[3.1.0 ...... lanarity on anti-HIV activity.

@en

North- and south-bicyclo[3.1.0 ...... lanarity on anti-HIV activity.

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type

Item

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North- and south-bicyclo[3.1.0 ...... lanarity on anti-HIV activity.

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North- and south-bicyclo[3.1.0 ...... lanarity on anti-HIV activity.

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North- and south-bicyclo[3.1.0 ...... lanarity on anti-HIV activity.

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North- and south-bicyclo[3.1.0 ...... lanarity on anti-HIV activity.

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P1476

North- and south-bicyclo[3.1.0 ...... planarity on anti-HIV activity

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P2093

B Christie Vu

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Christopher C Lai

http://www.w3.org/2001/XMLSchema#string

Dina M Sigano

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James A Kelley

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Maria J Gonzalez-Moa

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Pamela L Russ

http://www.w3.org/2001/XMLSchema#string

Stephen H Hughes

http://www.w3.org/2001/XMLSchema#string

Victor E Marquez

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P2860

Mechanism of inhibition of the human immunodeficiency virus type 1 reverse transcriptase by d4TTP: an equivalent incorporation efficiency relative to the natural substrate dTTP

Replication of phenotypically mixed human immunodeficiency virus type 1 virions containing catalytically active and catalytically inactive reverse transcriptase.

Correlation between preferred sugar ring conformation and activity of nucleoside analogues against human immunodeficiency virus.

A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1

Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivo

Implication of the tRNA initiation step for human immunodeficiency virus type 1 reverse transcriptase in the mechanism of 3'-azido-3'-deoxythymidine (AZT) resistance.

The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants.

Fixed conformation nucleoside analogs effectively inhibit excision-proficient HIV-1 reverse transcriptases.

Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker.

Nucleosides with a twist. Can fixed forms of sugar ring pucker influence biological activity in nucleosides and oligonucleotides?

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1354-1363

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scholarly article

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10.1002/CMDC.200900153

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Jeffrey R. Deschamps

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2009-08-01T00:00:00Z

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26298873

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19533724

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HIV

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6776084

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North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.

about

P2860

P2860

North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.

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