The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.
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SWI/SNF complexes containing Brahma or Brahma-related gene 1 play distinct roles in smooth muscle development.ATP-dependent chromatin remodeling complexes as novel targets for cancer therapyFulvestrant induces resistance by modulating GPER and CDK6 expression: implication of methyltransferases, deacetylases and the hSWI/SNF chromatin remodelling complexEpigenetics in cancerThe SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferationp53-mediated heterochromatin reorganization regulates its cell fate decisions.The H3K27me3 demethylase UTX in normal development and disease.Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cellsBRG1 is a prognostic marker and potential therapeutic target in human breast cancer.A bioinformatics workflow for variant peptide detection in shotgun proteomicsBrg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation.ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancersSWItching on the transcriptional circuitry in melanoma.SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27.Two novel BRM insertion promoter sequence variants are associated with loss of BRM expression and lung cancer risk.Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.Chromatin Remodeling Factor Brg1 Supports the Early Maintenance and Late Responsiveness of Nestin-Lineage Adult Neural Stem and Progenitor Cells.Discovery of BRM Targeted Therapies: Novel Reactivation of an Anti-cancer GeneBRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 lossTumor necrosis factor α-induced hypoxia-inducible factor 1α-β-catenin axis regulates major histocompatibility complex class I gene activation through chromatin remodeling.β-Catenin C-terminal signals suppress p53 and are essential for artery formation.SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells.Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cellsHuman induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity.The clinicopathologic significance of p53 and BAF-250a (ARID1A) expression in clear cell carcinoma of the endometrium.Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein.Brahma-related gene 1 induces apoptosis in a p53-dependent manner in human rheumatoid fibroblast-like synoviocyte MH7AGenetic variant in SWI/SNF complexes influences hepatocellular carcinoma risk: a new clue for the contribution of chromatin remodeling in carcinogenesis.Mechanism of BRG1 silencing in primary cancers.The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A.Mammalian SWI/SNF Enzymes and the Epigenetics of Tumor Cell Metabolic Reprogramming.Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway.Epigenetic aberrations during oncogenesis.Diverse functions of ATP-dependent chromatin remodeling complexes in development and cancer.The dynamic interplay in chromatin remodeling factors polycomb and trithorax proteins in response to DNA damage.NFAT gene family in inflammation and cancer.Chromatin remodeler mutations in human cancers: epigenetic implications.Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance.The absence of Brm exacerbates photocarcinogenesis.
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P2860
The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
The SWI/SNF chromatin remodeli ...... liferation of malignant cells.
@en
The SWI/SNF chromatin remodeli ...... liferation of malignant cells.
@nl
type
label
The SWI/SNF chromatin remodeli ...... liferation of malignant cells.
@en
The SWI/SNF chromatin remodeli ...... liferation of malignant cells.
@nl
prefLabel
The SWI/SNF chromatin remodeli ...... liferation of malignant cells.
@en
The SWI/SNF chromatin remodeli ...... liferation of malignant cells.
@nl
P2093
P2860
P356
P1433
P1476
The SWI/SNF chromatin remodeli ...... oliferation of malignant cells
@en
P2093
A N Imbalzano
S R Grossman
P2860
P2888
P304
P356
10.1038/ONC.2009.121
P407
P577
2009-05-18T00:00:00Z