CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. - Wikidata - wikimedia - TriplyDB

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

http://www.wikidata.org/entity/Q39862482

about

Human single-stranded DNA binding proteins are essential for maintaining genomic stability Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks DNA resection in eukaryotes: deciding how to fix the break Genome-wide association study of intracranial aneurysm identifies three new risk loci Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability DNA double-strand break repair pathway choice and cancer The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining CtIP Mutations Cause Seckel and Jawad Syndromes BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51.Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination The DNA Damage Response: Making It Safe to Play with Knives Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.Regulation of repair choice: Cdk1 suppresses recruitment of end joining factors at DNA breaks.Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases.Differential requirement for SUB1 in chromosomal and plasmid double-strand DNA break repair Processing of damaged DNA ends for double-strand break repair in mammalian cells Replication fork instability and the consequences of fork collisions from rereplication Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins EXD2 promotes homologous recombination by facilitating DNA end resection MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability A dual role for A-type lamins in DNA double-strand break repair BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis Microhomology-mediated end joining: new players join the team Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage The intersection between DNA damage response and cell death pathways Homologs of breast cancer genes in plants Pathogenesis of chagas' disease: parasite persistence and autoimmunity Expanded roles of the Fanconi anemia pathway in preserving genomic stability Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks Mechanisms for Structural Variation in the Human Genome Homozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks.And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting Genome-wide transcriptome profiling of homologous recombination DNA repair.The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis

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P2860

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

http://www.wikidata.org/entity/Q39862482

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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name

CtIP-BRCA1 modulates the choic ...... way throughout the cell cycle.

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CtIP-BRCA1 modulates the choic ...... way throughout the cell cycle.

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CtIP-BRCA1 modulates the choic ...... way throughout the cell cycle.

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CtIP-BRCA1 modulates the choic ...... way throughout the cell cycle.

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CtIP-BRCA1 modulates the choic ...... hway throughout the cell cycle

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P2860

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

CDK targets Sae2 to control DNA-end resection and homologous recombination

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

Human CtIP promotes DNA end resection

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

Genetic steps of mammalian homologous repair with distinct mutagenic consequences

Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency

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