The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
about
Hepatitis C virus NS5A protein modulates transcription through a novel cellular transcription factor SRCAPNuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressorFunctional link of BRCA1 and ataxia telangiectasia gene product in DNA damage responseA novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteinsBRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activityStructure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structureBRCA1 and FOXA1 proteins coregulate the expression of the cell cycle-dependent kinase inhibitor p27(Kip1)Human SIRT6 promotes DNA end resection through CtIP deacetylationCtIP is required to initiate replication-dependent interstrand crosslink repairThe UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic functionRAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sitesDNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domainsHighlight: BRCA1 and BRCA2 proteins in breast cancerTranscriptional regulation of BRCA1 expression by a metabolic switchPALB2 is an integral component of the BRCA complex required for homologous recombination repairN terminus of CtIP is critical for homologous recombination-mediated double-strand break repairMERIT40 facilitates BRCA1 localization and DNA damage repairCCDC98 targets BRCA1 to DNA damage sitesThe 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor geneNet, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation.Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of splitHuman CtIP promotes DNA end resectionStructural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1ZEB represses transcription through interaction with the corepressor CtBPDNA end resection: many nucleases make light workCBP/p300 interact with and function as transcriptional coactivators of BRCA1JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interactionBRCA1 interacts with components of the histone deacetylase complexUse of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1.BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells.Role of BRCA gene dysfunction in breast and ovarian cancer predisposition.Molecular mechanisms of etoposideBRCA1, a 'complex' protein involved in the maintenance of genomic stabilityRepair of strand breaks by homologous recombinationStructural consequences of a cancer-causing BRCA1-BRCT missense mutationPathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach53BP1 regulates DSB repair using Rif1 to control 5' end resectionHomologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins
P2860
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P2860
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The C-terminal (BRCT) domains ...... of transcriptional repression
@ast
The C-terminal (BRCT) domains ...... of transcriptional repression
@en
The C-terminal (BRCT) domains ...... of transcriptional repression
@nl
type
label
The C-terminal (BRCT) domains ...... of transcriptional repression
@ast
The C-terminal (BRCT) domains ...... of transcriptional repression
@en
The C-terminal (BRCT) domains ...... of transcriptional repression
@nl
prefLabel
The C-terminal (BRCT) domains ...... of transcriptional repression
@ast
The C-terminal (BRCT) domains ...... of transcriptional repression
@en
The C-terminal (BRCT) domains ...... of transcriptional repression
@nl
P2093
P2860
P3181
P356
P1476
The C-terminal (BRCT) domains ...... of transcriptional repression
@en
P2093
P2860
P304
25388-25392
P3181
P356
10.1074/JBC.273.39.25388
P407
P577
1998-09-01T00:00:00Z