Autophagy protects neuron from Abeta-induced cytotoxicity.
about
Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron DegenerationThe role of mTOR signaling in Alzheimer diseaseCilostazol Modulates Autophagic Degradation of β-Amyloid Peptide via SIRT1-Coupled LKB1/AMPKα Signaling in Neuronal CellsInternalized gap junctions are degraded by autophagyNicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.Regulation of amyloid precursor protein processing by the Beclin 1 complexNovel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the α7nAch receptor in SH-SY5Y cells.Drug candidates in clinical trials for Alzheimer's disease.Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits.Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells3-n-Butylphthalide (NBP) attenuated neuronal autophagy and amyloid-β expression in diabetic mice subjected to brain ischemia.Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human diseaseAβ1-42 monomers or oligomers have different effects on autophagy and apoptosisShort-term fasting induces profound neuronal autophagyInduction of autophagy by a novel small molecule improves aβ pathology and ameliorates cognitive deficitsThe polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology.Roles of autophagy in MPP+-induced neurotoxicity in vivo: the involvement of mitochondria and α-synuclein aggregationHippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathologyAutophagy in dementias.Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta₂₅₋₃₅ via the Autophagy PathwayCilostazol Upregulates Autophagy via SIRT1 Activation: Reducing Amyloid-β Peptide and APP-CTFβ Levels in Neuronal CellsAutophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex.APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease.Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death.Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseasesNeuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux.Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cellsAmyloidosis in Alzheimer's Disease: The Toxicity of Amyloid Beta (A β ), Mechanisms of Its Accumulation and Implications of Medicinal Plants for TherapyRapamycin, Autophagy, and Alzheimer's DiseaseProteins and mechanisms regulating gap-junction assembly, internalization, and degradation.Cell "self-eating" (autophagy) mechanism in Alzheimer's disease.Degradation of connexins and gap junctions.Autophagy in Alzheimer's disease.Autophagy: a double-edged sword in Alzheimer's disease.Degradation of endocytosed gap junctions by autophagosomal and endo-/lysosomal pathways: a perspectiveSirtuins' modulation of autophagy.Protein recycling pathways in neurodegenerative diseases.
P2860
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P2860
Autophagy protects neuron from Abeta-induced cytotoxicity.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Autophagy protects neuron from Abeta-induced cytotoxicity.
@en
Autophagy protects neuron from Abeta-induced cytotoxicity.
@nl
type
label
Autophagy protects neuron from Abeta-induced cytotoxicity.
@en
Autophagy protects neuron from Abeta-induced cytotoxicity.
@nl
prefLabel
Autophagy protects neuron from Abeta-induced cytotoxicity.
@en
Autophagy protects neuron from Abeta-induced cytotoxicity.
@nl
P2093
P356
P1433
P1476
Autophagy protects neuron from Abeta-induced cytotoxicity.
@en
P2093
Houng-Chi Liou
Shih-Ya Hung
Wei-Pang Huang
Wen-Mei Fu
P304
P356
10.4161/AUTO.5.4.8096
P577
2009-05-06T00:00:00Z