TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway. - Wikidata - wikimedia - TriplyDB

TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.

TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.

http://www.wikidata.org/entity/Q39885215

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The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice Mouse models of intestinal cancer Colorectal cancer models for novel drug discovery Animal models of colorectal cancer In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei Synthetic lethal therapy for KRAS mutant non-small-cell lung carcinoma with nanoparticle-mediated CDK4 siRNA delivery Prediction and testing of biological networks underlying intestinal cancer Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells.Genetic and Chemical Models of Colorectal Cancer in Mice.Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.A reciprocal role of prostate cancer on stromal DNA damage.Animal models of gastrointestinal and liver diseases. New mouse models for studying dietary prevention of colorectal cancer Temporal dissection of K-ras(G12D) mutant in vitro and in vivo using a regulatable K-ras(G12D) mouse allele Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis The utility of Apc-mutant rats in modeling human colon cancer.Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut.Vicious cycle of TGF-β signaling in tumor progression and metastasis.PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling.MicroRNA-301a promotes migration and invasion by targeting TGFBR2 in human colorectal cancer.β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors.The landscape of somatic chromosomal copy number aberrations in GEM models of prostate carcinoma.Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation.Pathology of rodent models of intestinal cancer: progress report and recommendations Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasis The crosstalk of RAS with the TGF-β family during carcinoma progression and its implications for targeted cancer therapy.Anti-fibrogenic strategies and the regression of fibrosis.Regulation of homeostasis and oncogenesis in the intestinal epithelium by Ras.Mysteries of TGF-β Paradox in Benign and Malignant Cells.Role of MTA1 in head and neck cancers.Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool.Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion.A recellularized human colon model identifies cancer driver genes.TGF-β signaling in liver and gastrointestinal cancers TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function Inactivation of TGF-β signaling and loss of PTEN cooperate to induce colon cancer in vivo No back seat for a progression event-K-RAS as a therapeutic target in CRC.Differentiated intestinal epithelial cells express high levels of TGF-β receptors and exhibit increased sensitivity to growth inhibition.Three-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model.

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TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.

http://www.wikidata.org/entity/Q39885215

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2009 nî lūn-bûn

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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TGF-beta receptor inactivation ...... a-catenin-independent pathway.

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TGF-beta receptor inactivation ...... a-catenin-independent pathway.

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TGF-beta receptor inactivation ...... a-catenin-independent pathway.

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TGF-beta receptor inactivation ...... a-catenin-independent pathway.

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TGF-beta receptor inactivation ...... a-catenin-independent pathway.

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TGF-beta receptor inactivation ...... a-catenin-independent pathway.

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J.GASTRO.2009.01.066

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Gastroenterology

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TGF-beta receptor inactivation ...... a-catenin-independent pathway.

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Andres Rojas

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Cornelia M Ulrich

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Karen D Tsuchiya

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M Kay Washington

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Nina M Munoz

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Patty Trobridge

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Senji Shirasawa

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Sue Knoblaugh

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Takehiko Sasazuki

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William M Grady

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P2860

The Hallmarks of Cancer

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

TGFbeta signaling in growth control, cancer, and heritable disorders

TGFbeta and Wnt pathway cross-talk

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

TGF and Wnt pathway cross-talk

TGF-β signaling in T cells: roles in lymphoid and epithelial neoplasia

TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.

To cycle or not to cycle: a critical decision in cancer.

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