Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.
about
A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma.Differential proteomics identification of HSP90 as potential serum biomarker in hepatocellular carcinoma by two-dimensional electrophoresis and mass spectrometry.Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model.Targeting cMET with INC280 impairs tumour growth and improves efficacy of gemcitabine in a pancreatic cancer modelSTAT5b as molecular target in pancreatic cancer--inhibition of tumor growth, angiogenesis, and metastases.Targeting the mTOR pathway using deforolimus in cancer therapy.Molecular basis for the actions of Hsp90 inhibitors and cancer therapy.Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever.[Challenges in the organization of investigator initiated trials: in transplantation medicine].Heat shock proteins in hepatocellular carcinoma: Molecular mechanism and therapeutic potential.mTOR inhibition improves fibroblast growth factor receptor targeting in hepatocellular carcinoma.Targeting HSF1 sensitizes cancer cells to HSP90 inhibition.Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models.Advanced retinoblastoma treatment: targeting hypoxia by inhibition of the mammalian target of rapamycin (mTOR) in LH(BETA)T(AG) retinal tumors.Insights from yeast into whether the inhibition of heat shock transcription factor (Hsf1) by rapamycin can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor.Trim14 overexpression causes the same transcriptional changes in mouse embryonic stem cells and human HEK293 cells.A phase II trial of bevacizumab plus temsirolimus in patients with advanced hepatocellular carcinoma.Hsp90 inhibition enhances PI-3 kinase inhibition and radiosensitivity in glioblastoma.
P2860
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P2860
Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
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name
Targeting heat-shock protein 9 ...... atocellular carcinoma in mice.
@en
Targeting heat-shock protein 9 ...... atocellular carcinoma in mice.
@nl
type
label
Targeting heat-shock protein 9 ...... atocellular carcinoma in mice.
@en
Targeting heat-shock protein 9 ...... atocellular carcinoma in mice.
@nl
prefLabel
Targeting heat-shock protein 9 ...... atocellular carcinoma in mice.
@en
Targeting heat-shock protein 9 ...... atocellular carcinoma in mice.
@nl
P2093
P2860
P356
P1433
P1476
Targeting heat-shock protein 9 ...... atocellular carcinoma in mice.
@en
P2093
Christian Moser
Claus Hellerbrand
Edward K Geissler
Hans J Schlitt
Oliver Stoeltzing
Philipp Schachtschneider
Stefan Fichnter-Feigl
Sven A Lang
Volker Schmitz
P2860
P304
P356
10.1002/HEP.22685
P407
P577
2009-02-01T00:00:00Z