Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer
about
Targeting β-tubulin:CCT-β complexes incurs Hsp90- and VCP-related protein degradation and induces ER stress-associated apoptosis by triggering capacitative Ca2+ entry, mitochondrial perturbation and caspase overactivation.Heat shock protein 90 inhibition abrogates hepatocellular cancer growth through cdc2-mediated G2/M cell cycle arrest and apoptosis.Differential proteomics identification of HSP90 as potential serum biomarker in hepatocellular carcinoma by two-dimensional electrophoresis and mass spectrometry.Molecular Pathogenesis of Hepatitis-B-virus-associated Hepatocellular Carcinoma.Split Renilla luciferase protein fragment-assisted complementation (SRL-PFAC) to characterize Hsp90-Cdc37 complex and identify critical residues in protein/protein interactions.Withaferin A targets heat shock protein 90 in pancreatic cancer cells.Chronic hepatitis B in hepatocarcinogenesisHSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells.Chromosome region maintenance 1 expression and its association with clinical pathological features in primary carcinoma of the liver.New insights on the role of epigenetic alterations in hepatocellular carcinoma.Targeting the oncogene and kinome chaperone CDC37.Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein.Oval cell proliferation in p16INK4a expressing mouse liver is triggered by chronic growth stimuli.Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transitionGenetic and epigenetic control of molecular alterations in hepatocellular carcinoma.Targeting GRP75 improves HSP90 inhibitor efficacy by enhancing p53-mediated apoptosis in hepatocellular carcinoma.Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease.Human telomerase inhibitors from microbial source.Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteinsComputational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling.Novel celastrol derivatives inhibit the growth of hepatocellular carcinoma patient-derived xenografts.Activation of v-Myb avian myeloblastosis viral oncogene homolog-like2 (MYBL2)-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of hepatocellular carcinoma with mutant p53.Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease.Focal loss of long non-coding RNA-PRAL, as determinant of cell function and phenotype of hepatocellular carcinoma.Suppressing the CDC37 cochaperone in hepatocellular carcinoma cells inhibits cell cycle progression and cell growth.Interaction of major genes predisposing to hepatocellular carcinoma with genes encoding signal transduction pathways influences tumor phenotype and prognosis.Black currant phytoconstituents exert chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis by suppression of the inflammatory response.Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma.An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis.
P2860
Q30532061-4648AED3-0730-4DE7-A133-491ACF0DB2A4Q30585904-4B1832DA-A464-4474-8987-36BE67505BCEQ33580269-2B13F75F-304D-45E3-81BB-F633DDFA1254Q33855801-66E9342A-0F7B-4B69-9B22-B484CB827FD1Q33966866-E68D643D-699E-411E-90E6-BAC16E7F4380Q35004306-521825F8-656D-4D09-9053-D25DE92BDA61Q36557635-04160B2A-E5B8-4935-834F-17CDBC400CE6Q36956034-F9737452-9273-45BE-A2F1-88D9DD90F936Q37002035-462FE9EF-1553-4675-9C19-E7C2A36CF36CQ37031728-046F93DE-08ED-4755-8422-641D6E5A0E0FQ37177064-1AE2DB43-CF3F-4EF5-B57F-94268A160FD6Q37269298-C17415B6-33B2-45E5-AA0B-D6F65595F200Q37293878-4A3F4DCB-856E-4449-8DF2-5308BB0B5296Q37464190-98B560C6-8DBF-47C5-AFBD-939586B86664Q37476446-6BDC00BE-5421-4E57-9C6D-57488077DDCBQ37490724-131E22BC-2373-4051-BCAF-52C93A59568EQ37580201-961F325B-59EC-4652-8C7A-2EA467C21E53Q38541173-7C35837F-E45E-4D52-A54B-2349485F9763Q38725015-563170DE-A1BA-48DC-88D1-7E6BD3AF73EFQ38913419-CEEF3A2D-63EA-4C49-8418-DC15D68EB1AAQ38972744-886BE8A5-2BBB-464D-99C7-035E9FBAA6B4Q39561085-43018514-980F-44CD-94A9-3A0FED1EE0CAQ39904702-A8C46720-2F18-4248-BB3F-534AE264AD95Q39968256-4130E7A2-55CC-41EC-9663-FD6F9265D8EEQ41918261-05BCC3DA-D3FF-4873-BA05-8DF659D32DB3Q42202989-C529A307-E134-40A4-B4CA-C779AD460FD8Q42616887-48F7C735-37F0-40B9-A7D1-66066F983C5AQ45227714-DF5A2883-1BD7-43E7-BD40-94D1EBB2E406Q46012957-FB3392CD-5C93-4257-9749-044395AB12DAQ54318224-55261040-BD4D-42FC-A991-494B37BA84B0
P2860
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/01)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في ديسمبر 2005)
@ar
name
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@ast
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@en
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@nl
type
label
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@ast
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@en
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@nl
prefLabel
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@ast
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@en
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@nl
P2093
P3181
P356
P1433
P1476
Role of HSP90, CDC37, and CRM1 ...... genesis and human liver cancer
@en
P2093
Diego F. Calvisi
Francesco Feo
Lucia Daino
Maddalena Frau
Maria A. Seddaiu
Maria D. Muntoni
Maria M. Simile
Maria R. De Miglio
Maria R. Muroni
Rosa M. Pascale
P2860
P304
P3181
P356
10.1002/HEP.20962
P407
P577
2005-12-01T00:00:00Z