Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway.
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The cytoplasmic domain of neuropilin-1 regulates focal adhesion turnoverNeuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cellsCAS proteins in normal and pathological cell growth controlNeuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivityNeuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged miceNSP-CAS Protein Complexes: Emerging Signaling Modules in CancerStructural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocketNeuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironmentNeuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells.VEGF targets the tumour cell.PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin.Secretome signature of invasive glioblastoma multiformeOcta-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumorsA Novel Physiological Glycosaminoglycan-Deficient Splice Variant of Neuropilin-1 Is Anti-Tumorigenic In Vitro and In Vivo.Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling.How neuropilin-1 regulates receptor tyrosine kinase signalling: the knowns and known unknowns.Neuropilin signalling in angiogenesis.Neuropilin 1: function and therapeutic potential in cancer.The emerging role of class-3 semaphorins and their neuropilin receptors in oncology.Pleiotrophin exerts its migration and invasion effect through the neuropilin-1 pathwayDetailed characterization of the O-linked glycosylation of the neuropilin-1 c/MAM-domain.Methoxypoly(ethylene glycol)-block-poly(L-glutamic acid)-loaded cisplatin and a combination with iRGD for the treatment of non-small-cell lung cancers.Cationic Peptides and Peptidomimetics Bind Glycosaminoglycans as Potential Sema3A Pathway Inhibitors.Glycosylation-dependent galectin-1/neuropilin-1 interactions promote liver fibrosis through activation of TGF-β- and PDGF-like signals in hepatic stellate cells.Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas.Neuropilin-1 (NRP-1)/GIPC1 pathway mediates glioma progression.Polysialic acid on neuropilin-2 is exclusively synthesized by the polysialyltransferase ST8SiaIV and attached to mucin-type o-glycans located between the b2 and c domain.Multifaceted Role of Neuropilins in the Immune System: Potential Targets for ImmunotherapyNeuropilin-1 is a glial cell line-derived neurotrophic factor receptor in glioblastoma.Dually modified transmembrane proteoglycans in development and disease.N-terminal modification of VEGF-A C terminus-derived peptides delineates structural features involved in neuropilin-1 binding and functional activity.VEGF (Vascular Endothelial Growth Factor) Induces NRP1 (Neuropilin-1) Cleavage via ADAMs (a Disintegrin and Metalloproteinase) 9 and 10 to Generate Novel Carboxy-Terminal NRP1 Fragments That Regulate Angiogenic Signaling.
P2860
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P2860
Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Chondroitin sulphate-modified ...... gh a p130Cas-mediated pathway.
@en
Chondroitin sulphate-modified ...... gh a p130Cas-mediated pathway.
@nl
type
label
Chondroitin sulphate-modified ...... gh a p130Cas-mediated pathway.
@en
Chondroitin sulphate-modified ...... gh a p130Cas-mediated pathway.
@nl
prefLabel
Chondroitin sulphate-modified ...... gh a p130Cas-mediated pathway.
@en
Chondroitin sulphate-modified ...... gh a p130Cas-mediated pathway.
@nl
P2093
P2860
P356
P1433
P1476
Chondroitin sulphate-modified ...... ugh a p130Cas-mediated pathway
@en
P2093
Ian C Zachary
Lili Cheng
Michelle L Tickner
Paul Frankel
Pauliina Lehtolainen
P2860
P304
P356
10.1038/EMBOR.2008.151
P577
2008-08-15T00:00:00Z