Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins. - Wikidata - wikimedia - TriplyDB

Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins.

Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins.

http://www.wikidata.org/entity/Q39954297

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Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve Small-molecule SMAC mimetics as new cancer therapeutics Current Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible Crosstalk A small molecule SMAC mimic LBW242 potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cells Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition Usp18 regulates epidermal growth factor (EGF) receptor expression and cancer cell survival via microRNA-7.Neuronal transcription factors induce conversion of human glioma cells to neurons and inhibit tumorigenesis.Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML Calanquinone A induces anti-glioblastoma activity through glutathione-involved DNA damage and AMPK activation.A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis, and chemoresistance LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling Emerging insights into the molecular and cellular basis of glioblastoma.USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.Blockade of Inhibitors of Apoptosis Proteins in Combination with Conventional Chemotherapy Leads to Synergistic Antitumor Activity in Medulloblastoma and Cancer Stem-Like Cells.Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma.BIRC3 is a novel driver of therapeutic resistance in Glioblastoma.Antagonism of inhibitor of apoptosis proteins increases bone metastasis via unexpected osteoclast activation Simultaneous reconstruction of multiple signaling pathways via the prize-collecting steiner forest problem Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network.Targeting inhibitor of apoptosis proteins in combination with ErbB antagonists in breast cancer.Combination therapy for malignant glioma based on PTEN status.NDRG4 is required for cell cycle progression and survival in glioblastoma cells.Changes in caregiver perceptions over time in response to providing care for a loved one with a primary malignant brain tumor.Immunotherapy of pediatric brain tumor patients should include an immunoprevention strategy: a medical hypothesis paper Apoptosis repressor with caspase recruitment domain is regulated by MAPK/PI3K and confers drug resistance and survival advantage to AML.PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals Anti-cancer IAP antagonists promote bone metastasis: a cautionary tale.MicroRNAs and glioblastoma: roles in core signalling pathways and potential clinical implications.Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets.Ariadne's ChemEffect and Pathway Studio knowledge base.How to train glioma cells to die: molecular challenges in cell death.Elucidation of the genetic and epigenetic landscape alterations in RNA binding proteins in glioblastoma.Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer Therapy.Insights into molecular therapy of glioma: current challenges and next generation blueprint Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs.Inhibitor of Apoptosis Proteins: Promising Targets for Cancer Therapy.Computational approaches for drug repositioning and combination therapy design.Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas.Apoptotic Signaling Pathways in Glioblastoma and Therapeutic Implications.

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Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins.

http://www.wikidata.org/entity/Q39954297

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Resistance of human glioblasto ...... hibitor of apoptosis proteins.

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Resistance of human glioblasto ...... hibitor of apoptosis proteins.

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type

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Resistance of human glioblasto ...... hibitor of apoptosis proteins.

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Resistance of human glioblasto ...... hibitor of apoptosis proteins.

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prefLabel

Resistance of human glioblasto ...... hibitor of apoptosis proteins.

@en

Resistance of human glioblasto ...... hibitor of apoptosis proteins.

@nl

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Journal of Clinical Investigation

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Resistance of human glioblasto ...... hibitor of apoptosis proteins.

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P2093

Leigh Zawel

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Mary A Tran

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Monish Jain

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Renee D Wright

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Santosh Kesari

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P2860

A human IAP-family gene, apollon, expressed in human brain cancer cells

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

Identification of human brain tumour initiating cells

Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

Down-regulation of ARC contributes to vulnerability of hippocampal neurons to ischemia/hypoxia

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

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3109-3122

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118

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Madeleine Lemieux

David S Ziegler

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2008-09-01T00:00:00Z

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18677408

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apoptotic process

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2491457

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