about
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesisSmall-molecule inhibition of BRDT for male contraception.Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signalingSirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cellsSelective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoterMammalian SIRT1 represses forkhead transcription factorsBET bromodomain inhibition as a therapeutic strategy to target c-MycMediator kinase inhibition further activates super-enhancer-associated genes in AMLNSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism.Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells.Differentiation of NUT midline carcinoma by epigenomic reprogramming.Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformationBET bromodomains mediate transcriptional pause release in heart failureDifferential disruption of EWS-FLI1 binding by DNA-binding agents.Mice heterozygous for CREB binding protein are hypersensitive to γ-radiation and invariably develop myelodysplastic/myeloproliferative neoplasmStable inhibitory activity of regulatory T cells requires the transcription factor HeliosGlucocorticoids enhance muscle endurance and ameliorate Duchenne muscular dystrophy through a defined metabolic programH3K79 methylation profiles define murine and human MLL-AF4 leukemias.Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo.Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis.The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells.Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins.Systematic in vivo structure-function analysis of p300 in hematopoiesis.Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.The Sirt1 deacetylase modulates the insulin-like growth factor signaling pathway in mammalsMacrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repairCondensin II protein dysfunction impacts mitochondrial respiration and mitochondrial oxidative stress responsesBPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathwayCorrection: BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathwayHigh-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing SarcomaCombined targeting of the BRD4-NUT-p300 axis in NUT midline carcinoma by dual selective bromodomain inhibitor, NEO2734
P50
Q24540613-50C55769-C706-402B-B28F-28CBEC206443Q24616901-628B6AF9-9BEE-4C8B-84DD-58EBDDBE319CQ24632740-52BABDBE-1276-40D5-823E-A13A14C8C94CQ24810302-CD6FFC53-5C41-4DFA-9C3C-F3F993E0140DQ28144132-C58A4409-F3CB-4FB4-A242-CAD24D053FDCQ28246430-7A458A40-588E-4E02-AFD3-87BF03B6D4F5Q28247024-E628C146-0AA0-4D19-BBAD-A1F14940A910Q28267938-1E3C5BF4-D86C-454F-AE8D-D1BBC50CA525Q30586112-1B8172E3-742D-4403-AC7C-7861934BBB7CQ34013832-545A728C-F417-40E8-9AE1-E78D38B5708FQ34174143-FAA49879-7AE8-400B-80E2-1496767783F1Q34213023-70CFF237-5373-4A09-A4CB-F33C45C77A1CQ34361491-B0D5BED4-484C-4145-BE06-7BCB1D8D1143Q34874355-A2405C88-38D6-4DF0-AE0D-DB4E970ADF43Q36108482-3C260FDC-F0C0-4A3B-959F-9C243742E508Q36233090-FB8AB3D7-912F-4DD2-A9DB-C2DD75123B21Q36371465-A8D1944B-E850-4C69-874D-78E8CAAA16C4Q36991857-B1F43C08-5562-465C-BDF7-D3AF854CF018Q37021808-2D44D96D-877A-4B83-9B91-2BD12C8CCBF0Q37132758-108A6680-7969-4E64-830A-CB8A4BE42394Q37724187-F9EEFA5F-0933-4B62-A07A-DD5C0534264CQ39954297-21CDFF5E-F839-4956-AE6D-07646A8488A3Q43262980-626F83FB-5E98-4552-A345-0FDF6D3B319FQ45141257-8FCAF406-6940-4D27-9061-3FC123789B42Q59560361-C5971973-7C06-4C44-AA62-95E3E3026C2BQ89454243-745A0BB5-0D59-4620-ACAC-D3F71E7E5C20Q90949861-AAFC50D6-09BC-4158-A1E0-B235C7B6C0D7Q92025487-6FC4E6AF-31FA-4D2E-B0CC-6406C26DBCE5Q92860806-55E71823-2B0F-40BD-BD56-8BAE10F54BBEQ93064614-2390FFD6-0346-40DB-9D0E-7FB97BF29510Q94552514-4D8D6C96-2999-4E4B-AB69-7F9D1ED11173
P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Madeleine Lemieux
@ast
Madeleine Lemieux
@en
Madeleine Lemieux
@es
Madeleine Lemieux
@nl
Madeleine Lemieux
@sl
type
label
Madeleine Lemieux
@ast
Madeleine Lemieux
@en
Madeleine Lemieux
@es
Madeleine Lemieux
@nl
Madeleine Lemieux
@sl
prefLabel
Madeleine Lemieux
@ast
Madeleine Lemieux
@en
Madeleine Lemieux
@es
Madeleine Lemieux
@nl
Madeleine Lemieux
@sl
P106
P1153
24311641800
P21
P31
P496
0000-0001-6355-8691