Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity.
about
Progress toward overcoming hypoxia-induced resistance to solid tumor therapyPrinciples of Ligand Binding within a Completely Buried Cavity in HIF2α PAS-BHyperbaric oxygen preconditioning: a reliable option for neuroprotectionHeterogeneous role of the glutathione antioxidant system in modulating the response of ESFT to fenretinide in normoxia and hypoxiaHypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1AlphaNrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxiaSmall Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR SignalingExpression of MDR1, HIF-1α and MRP1 in sacral chordoma and chordoma cell line CM-319Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaBMolecular mechanisms of hypoxia in cancer.HIF-1α inhibition reverses multidrug resistance in colon cancer cells via downregulation of MDR1/P-glycoprotein.HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast.p53 Ser15 phosphorylation disrupts the p53-RPA70 complex and induces RPA70-mediated DNA repair in hypoxia.Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glycoprotein in human colon carcinoma tissue and cells.NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment.Review of high-dose intravenous vitamin C as an anticancer agent.Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel‑7402/5‑fluorouracil cells.The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism.Mahanine, a novel mitochondrial complex-III inhibitor induces G0/G1 arrest through redox alteration-mediated DNA damage response and regresses glioblastoma multiforme.Near-infrared dye loaded polymeric nanoparticles for cancer imaging and therapy and cellular response after laser-induced heatingThe role of hypoxia inducible factor-1 alpha in bypassing oncogene-induced senescenceHypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2HDAC4 protein regulates HIF1α protein lysine acetylation and cancer cell response to hypoxia.Association of Pretreatment Anemia with Pathological Response and Survival of Breast Cancer Patients Treated with Neoadjuvant Chemotherapy: A Population-Based StudyHypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells.Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp.Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancerNotch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells.Knockdown of the small conductance Ca(2+) -activated K(+) channels is potently cytotoxic in breast cancer cell lines.Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathwaysNZ51, a ring-expanded nucleoside analog, inhibits motility and viability of breast cancer cells by targeting the RNA helicase DDX3.Assessment of stanniocalcin-1 as a prognostic marker in human esophageal squamous cell carcinoma.The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistanceActivation of the PD-1/PD-L1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis.Hypoxia-inducible factor-targeting prodrug TOP3 combined with gemcitabine or TS-1 improves pancreatic cancer survival in an orthotopic modelHypoxia promotes the phenotypic change of aldehyde dehydrogenase activity of breast cancer stem cells.Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death.Targeting tumour angiogenesis with small molecule inhibitors of hypoxia inducible factor.
P2860
Q26796405-C135FA8E-1F1D-43FC-9FB8-0987DF2A1339Q27658400-09F5A653-7AB4-44A9-B748-BEE277713159Q28069280-C83CBA0E-B88D-4D04-BA48-3543AA09D2AEQ28478325-3A775E4D-5E4F-49B0-A54C-7DD1B417CB80Q28533909-05679844-F7DD-4482-9B20-F969D615F622Q28828596-E0ACDBE2-848B-4A87-95DD-09978C41BFD7Q28833656-5963D100-652B-43CD-A89F-BC595F059AA3Q33274001-D1B9B2B0-BAA2-4AEA-B51C-7CAF47E4B1C4Q33656653-4EA54031-B13F-43AA-87F8-CF712A89FFBAQ33705108-7F0846E5-EEF4-47FD-AB95-594EE4BF4A5EQ33717131-89932FB3-8540-4A0B-A10A-8F24D8BBC34BQ34118293-09EDF523-7A25-4FCC-A6F9-46DCDC89F040Q34144537-3CE26541-60B0-447A-8FA4-8A59A2BB7ABDQ34152742-5D30506E-AF4D-477E-AEBD-030E2CE16C54Q34377146-2D412958-118C-40F5-ABBC-3AC98D30D41DQ34406887-29A300FE-A176-4C7D-873C-AAAD1086D881Q34487968-02DA9F32-435E-423E-B841-9831637E1201Q34494886-EDFACC87-F89D-4D61-BA34-5B130F78F2DEQ34701603-E3D83CCD-AD5C-488A-BA17-A75D4C591E31Q34704811-84C0617D-A05A-41BA-A656-043D03A822F9Q35159236-C74DFED0-95D8-47BA-9BC6-49BC341DC0F8Q35199324-4364626A-2119-4DEA-AF30-8C576E982B4FQ35273305-D6F39DCF-73EC-447C-A54A-3E78480A8137Q35516124-864555F8-FBAE-4FB3-ACF4-D8EDE939E1DEQ35751128-35530F0A-9639-4256-AC21-3EEEA771E486Q35811243-F1B2F23E-9E6A-41AB-98B9-1DDF39728604Q35852614-776D437D-AE3F-4287-BA30-C32714E4F474Q36220497-9FF343AF-597E-45CB-A7CC-7F09904195A1Q36414386-1B910C42-93C0-4723-9782-3E1B5534C5EDQ36531433-8DFE8942-4A5B-4086-8B93-701B3EB6490BQ36533102-EED9C344-35D6-4DF1-A3D3-2BC27E07CCECQ36545995-6C1914CE-51E6-41F8-BED0-1134897B5CE2Q36557459-45E32E31-B48C-4A1C-93CE-1389A52E7181Q36642821-055FCAEE-E281-40AA-8C6D-09570B35F0CFQ36890663-8DEEC26C-E489-41BE-91D7-90E8D46432D9Q36963025-2FF4A8E4-D4FC-431A-ACD2-F397C8E9EE71Q37170729-9F6358FE-1BCA-4D22-AA40-B4C4BE1C02E2Q37735635-E369AA33-F5CA-4D99-9B1E-A0B2149173BFQ37745415-AEC0FB10-4AD1-4559-B92D-D82DDFC081FAQ37864096-541DFFAB-9E76-4D32-BF19-4D3342D6FD24
P2860
Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Hypoxia-induced resistance to ...... a-inducible factor-1 activity.
@en
Hypoxia-induced resistance to ...... a-inducible factor-1 activity.
@nl
type
label
Hypoxia-induced resistance to ...... a-inducible factor-1 activity.
@en
Hypoxia-induced resistance to ...... a-inducible factor-1 activity.
@nl
prefLabel
Hypoxia-induced resistance to ...... a-inducible factor-1 activity.
@en
Hypoxia-induced resistance to ...... a-inducible factor-1 activity.
@nl
P2093
P1476
Hypoxia-induced resistance to ...... a-inducible factor-1 activity.
@en
P2093
Charles H Graham
Geneviève C Paré
Lisa J Frederiksen
Richard Sullivan
P304
P356
10.1158/1535-7163.MCT-08-0198
P577
2008-07-01T00:00:00Z