Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins.

Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins.

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http://www.wikidata.org/entity/Q39967982
Bioactive lipids and the control of Bax pro-apoptotic activityLipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinibDeciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.Simvastatin reduces melanoma progression in a murine model.Lipid raft localization of epidermal growth factor receptor alters matrix metalloproteinase-1 expression in SiHa cells via the MAPK/ERK signaling pathway.Mevalonate kinase deficiency and neuroinflammation: balance between apoptosis and pyroptosis.The effect of statins on cancer cells--review.Simvastatin inhibits cancer cell growth by inducing apoptosis correlated to activation of Bax and down-regulation of BCL-2 gene expression.Combined inhibitory effects of celecoxib and fluvastatin on the growth of human hepatocellular carcinoma xenografts in nude mice.Lovastatin induces apoptosis through the mitochondrial pathway in an undifferentiated SH-SY5Y neuroblastoma cell line.Lovastatin protects chondrocytes derived from Wharton's jelly of human cord against hydrogen-peroxide-induced in vitro injury.Rosuvastatin induces apoptosis in CD4(+)CD28 (null) T cells in patients with acute coronary syndromes.
P2860

Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins.

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http://www.wikidata.org/entity/Q39967982
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
Statins activate a mitochondri ...... n the prenylation of proteins.
@en
Statins activate a mitochondri ...... n the prenylation of proteins.
@nl
type
label
Statins activate a mitochondri ...... n the prenylation of proteins.
@en
Statins activate a mitochondri ...... n the prenylation of proteins.
@nl
prefLabel
Statins activate a mitochondri ...... n the prenylation of proteins.
@en
Statins activate a mitochondri ...... n the prenylation of proteins.
@nl
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Statins activate a mitochondri ...... n the prenylation of proteins.
@en
P2093
P2860
P304
P31
P356
10.1016/J.FEBSLET.2008.06.034
P407
P433
P478
P50
P577
P5875
P698
P921