L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer.
about
Direct induction of chondrogenic cells from human dermal fibroblast culture by defined factorsOrganogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitorsA highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cellsThe multifaceted role of the vasculature in endochondral fracture repairWwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditionsArid5a cooperates with Sox9 to stimulate chondrocyte-specific transcriptionAltered mRNA Splicing, Chondrocyte Gene Expression and Abnormal Skeletal Development due to SF3B4 Mutations in Rodriguez Acrofacial DysostosisFunctional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11-A Bioinformatics and Molecular StudyHIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells.Inactivation of Patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program.Identification of an evolutionarily conserved regulatory element of the zebrafish col2a1a gene.Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways.MiR-146b is down-regulated during the chondrogenic differentiation of human bone marrow derived skeletal stem cells and up-regulated in osteoarthritis.Heterogeneous nuclear ribonucleoprotein A1 interacts with microRNA-34a to promote chondrogenic differentiation of mesenchymal stem cells.Gene expression profile in human induced pluripotent stem cells: Chondrogenic differentiation in vitro, part ASox2 uses multiple domains to associate with proteins present in Sox2-protein complexes.An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine EmbryosSynovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilageType II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes.Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.Generation of hyaline cartilaginous tissue from mouse adult dermal fibroblast culture by defined factorsActivation of NF-κB/p65 facilitates early chondrogenic differentiation during endochondral ossificationSOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters.Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)Nkx3.2 promotes primary chondrogenic differentiation by upregulating Col2a1 transcriptionEndogenous retinoids in mammalian growth plate cartilage: analysis and roles in matrix homeostasis and turnoverCartilage repair using human embryonic stem cell-derived chondroprogenitors.Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte.The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesisProfiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress.Evolutionarily conserved, growth plate zone-specific regulation of the matrilin-1 promoter: L-Sox5/Sox6 and Nfi factors bound near TATA finely tune activation by Sox9.PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cellsVertebrate skeletogenesisIn vivo genome-wide analysis of multiple tissues identifies gene regulatory networks, novel functions and downstream regulatory genes for Bapx1 and its co-regulation with Sox9 in the mammalian vertebral column.Establishing neural crest identity: a gene regulatory recipeHigh levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation.A 3D Porous Gelatin-Alginate-Based-IPN Acts as an Efficient Promoter of Chondrogenesis from Human Adipose-Derived Stem Cells.
P2860
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P2860
L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
L-Sox5 and Sox6 drive expressi ...... x9 to a far-upstream enhancer.
@en
L-Sox5 and Sox6 drive expressi ...... x9 to a far-upstream enhancer.
@nl
type
label
L-Sox5 and Sox6 drive expressi ...... x9 to a far-upstream enhancer.
@en
L-Sox5 and Sox6 drive expressi ...... x9 to a far-upstream enhancer.
@nl
prefLabel
L-Sox5 and Sox6 drive expressi ...... x9 to a far-upstream enhancer.
@en
L-Sox5 and Sox6 drive expressi ...... x9 to a far-upstream enhancer.
@nl
P2860
P356
P1476
L-Sox5 and Sox6 drive expressi ...... x9 to a far-upstream enhancer.
@en
P2093
Véronique Lefebvre
P2860
P304
P356
10.1128/MCB.00695-08
P407
P577
2008-06-16T00:00:00Z