Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation.
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International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligandsIntegrating the puzzle pieces: the current atomistic picture of phospholipid-G protein coupled receptor interactionsLPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptorMolecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂Autotaxin: structure-function and signalingRole of platelets in neuroinflammation: a wide-angle perspectiveNew members of the mammalian glycerophosphodiester phosphodiesterase family: GDE4 and GDE7 produce lysophosphatidic acid by lysophospholipase D activityTargeted deletion of LPA5 identifies novel roles for lysophosphatidic acid signaling in development of neuropathic painCharacterization of non-olfactory GPCRs in human sperm with a focus on GPR18Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors.International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.Lysophosphatidic Acid Is Associated with Atherosclerotic Plaque Instability by Regulating NF-κB Dependent Matrix Metalloproteinase-9 Expression via LPA2 in Macrophages.Type 2 scavenger receptor CD36 in platelet activation: the role of hyperlipemia and oxidative stress.LPA receptor signaling: pharmacology, physiology, and pathophysiology.Lysophospholipid receptor nomenclature review: IUPHAR Review 8.Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody responseLysophosphatidic acid in atherosclerotic diseasesLysophosphatidic acid-activated Cl- current activity in human systemic sclerosis skin fibroblastsA GPR18-based signalling system regulates IOP in murine eye.Aiming drug discovery at lysophosphatidic acid targets.N-arachidonyl-glycine modulates synaptic transmission in superficial dorsal hornProtection of neuroblastoma Neuro2A cells from hypoxia-induced apoptosis by cyclic phosphatidic acid (cPA).Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acidGPR92/LPA₅ lysophosphatidate receptor mediates megakaryocytic cell shape change induced by human atherosclerotic plaquesAutotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasisCombined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist.Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Uncovering unique roles of LPA receptors in the tumor microenvironment.Insights into the pharmacological relevance of lysophospholipid receptors.Lys39-Lysophosphatidate Carbonyl Oxygen Interaction Locks LPA1 N-terminal Cap to the Orthosteric Site and partners Arg124 During Receptor ActivationSo what do we call GPR18 now?Virtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions.Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.Lysophosphatidic acid-induced arterial wall remodeling: requirement of PPARgamma but not LPA1 or LPA2 GPCR.N-acyl amino acids and N-acyl neurotransmitter conjugates: neuromodulators and probes for new drug targets.Lysophosphatidic acid-1-receptor targeting agents for fibrosis.Endogenous metabolites as ligands for G protein-coupled receptors modulating risk factors for metabolic and cardiovascular disease.Comparative analyses of lysophosphatidic acid receptor-mediated signaling.
P2860
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P2860
Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation.
description
2009 nî lūn-bûn
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2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
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2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
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2009年學術文章
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name
Unique ligand selectivity of t ...... in human platelet activation.
@en
Unique ligand selectivity of t ...... in human platelet activation.
@nl
type
label
Unique ligand selectivity of t ...... in human platelet activation.
@en
Unique ligand selectivity of t ...... in human platelet activation.
@nl
prefLabel
Unique ligand selectivity of t ...... in human platelet activation.
@en
Unique ligand selectivity of t ...... in human platelet activation.
@nl
P2093
P2860
P356
P1476
Unique ligand selectivity of t ...... in human platelet activation.
@en
P2093
Abby L Parrill
Anna L Khandoga
Donna H Perygin
Gabor Tigyi
James I Fells
Jesica R Williams
Pankaj Goyal
Wolfgang Siess
Yuko Fujiwara
P2860
P304
17304-17319
P356
10.1074/JBC.M109.003194
P407
P577
2009-04-14T00:00:00Z