Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase.
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Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemiaBiological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB.A tyrosine kinase profile of prostate carcinomaStructural insights into the inhibited states of the Mer receptor tyrosine kinaseTargeting the TAM Receptors in LeukemiaIdentification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinaseIdentification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinasesEpithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactationA single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.TAM receptor tyrosine kinases: expression, disease and oncogenesis in the central nervous system.Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemiaTyro3 receptor tyrosine kinases in the heterogeneity of apoptotic cell uptake.TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation.Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib.The receptor tyrosine kinase MerTK activates phospholipase C gamma2 during recognition of apoptotic thymocytes by murine macrophages.TAM receptors in leukemia: expression, signaling, and therapeutic implications.Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress.Biology of the TAM receptors.Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia.MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL.Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.Role of Growth arrest-specific gene 6-Mer axis in multiple myeloma.Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme.DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer.Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblasts.Gas6-mediated survival in NIH3T3 cells activates stress signalling cascade and is independent of Ras.Monitoring signal transduction in cancer: tyrosine kinase gene expression profiling.An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: a mechanism for localizing guanine nucleotide-exchange factor action.Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activatMerTK is a novel therapeutic target in gastric cancer.Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase.
P2860
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P2860
Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Mitogenic signals and transfor ...... ated receptor tyrosine kinase.
@en
type
label
Mitogenic signals and transfor ...... ated receptor tyrosine kinase.
@en
prefLabel
Mitogenic signals and transfor ...... ated receptor tyrosine kinase.
@en
P2860
P356
P1476
Mitogenic signals and transfor ...... ated receptor tyrosine kinase.
@en
P2860
P304
P356
10.1128/MCB.15.12.6582
P407
P577
1995-12-01T00:00:00Z