Src-family kinases play an essential role in differentiation signaling downstream of macrophage colony-stimulating factor receptors mediating persistent phosphorylation of phospholipase C-gamma2 and MAP kinases ERK1 and ERK2.
about
Phase II study of dasatinib in patients with previously treated malignant mesothelioma (cancer and leukemia group B 30601): a brief reportThe PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMMLRole of Erk1/2 signaling in the regulation of neutrophil versus monocyte development in response to G-CSF and M-CSF.M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talk.Instructive role of M-CSF on commitment of bipotent myeloid cells involves ERK-dependent positive and negative signaling.PLCγ2 and PKC are important to myeloid lineage commitment triggered by M-SCF and G-CSF.Autologous serum improves yield and metabolic capacity of monocyte-derived hepatocyte-like cells: possible implication for cell transplantation.CSF-1-induced Src signaling can instruct monocytic lineage choice.
P2860
Q35840886-67EAD7A0-4CF3-4C98-AB09-74E95BED43D8Q36111614-9654BF94-459D-4DDC-8F5C-81D5705F6802Q36115892-16A1C85A-1D7C-4BB4-B681-AB2C7BF4680AQ37348266-BAEDCA91-A062-44AA-BB92-ACA3BBBD2460Q37808572-5FC16293-9832-4F2B-B8FD-6192E2389548Q38838269-73D5953A-159B-4C1E-B64E-9081DFABFE7FQ44802238-44678F35-35D7-49DF-89BA-CB43810B691FQ45812153-15794555-7E35-4FD7-9E12-15D0E5044024Q50457530-1A9E0132-BD65-4DF1-A4BA-59F29C448E72
P2860
Src-family kinases play an essential role in differentiation signaling downstream of macrophage colony-stimulating factor receptors mediating persistent phosphorylation of phospholipase C-gamma2 and MAP kinases ERK1 and ERK2.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Src-family kinases play an ess ...... and MAP kinases ERK1 and ERK2.
@en
type
label
Src-family kinases play an ess ...... and MAP kinases ERK1 and ERK2.
@en
prefLabel
Src-family kinases play an ess ...... and MAP kinases ERK1 and ERK2.
@en
P2093
P2860
P356
P1433
P1476
Src-family kinases play an ess ...... and MAP kinases ERK1 and ERK2.
@en
P2093
Bourgin-Hierle C
Gobert-Gosse S
Grasset MF
Mouchiroud G
P2860
P2888
P304
P356
10.1038/SJ.LEU.2404986
P577
2007-11-01T00:00:00Z
P5875
P6179
1025687446