DNA damage-induced immune response: Micronuclei provide key platform.

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DNA damage-induced immune response: Micronuclei provide key platform.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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DNA damage-induced immune response: Micronuclei provide key platform.

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DNA damage-induced immune response: Micronuclei provide key platform.

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DNA damage-induced immune response: Micronuclei provide key platform.

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P1476

DNA damage-induced immune response: Micronuclei provide key platform

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P2093

Nelson O Gekara

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P2860

cGAS is essential for cellular senescence.

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.

RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.

Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.

Catastrophic nuclear envelope collapse in cancer cell micronuclei.

DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity.

Mitotic progression following DNA damage enables pattern recognition within micronuclei.

cGAS surveillance of micronuclei links genome instability to innate immunity.

Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy.

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2999-3001

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scholarly article

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10.1083/JCB.201708069

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English

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P478

216

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P50

Nelson O Gekara

P577

2017-08-31T00:00:00Z

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P698

28860276

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P921

DNA damage

P932

5626557

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