Signal responsiveness of IkappaB kinases is determined by Cdc37-assisted transient interaction with Hsp90.
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Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging ProcessA20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activityHepatitis B virus polymerase suppresses NF-κB signaling by inhibiting the activity of IKKs via interaction with Hsp90βArsenic trioxide exerts antimyeloma effects by inhibiting activity in the cytoplasmic substrates of histone deacetylase 6Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complexStat1 nuclear translocation by nucleolin upon monocyte differentiation.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesDifferential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52.A splicing variant of NME1 negatively regulates NF-κB signaling and inhibits cancer metastasis by interacting with IKKβNF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity.InterAKTions with FKBPs--mutational and pharmacological exploration.The IκB kinase complex in NF-κB regulation and beyond.FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma.HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death.Tunable signal processing through a kinase control cycle: the IKK signaling nodeNitric oxide suppresses LPS-induced inflammation in a mouse asthma model by attenuating the interaction of IKK and Hsp90.Poxvirus MC160 protein utilizes multiple mechanisms to inhibit NF-kappaB activation mediated via components of the tumor necrosis factor receptor 1 signal transduction pathway.Heat shock proteins 27 and 70 regulating angiotensin II-induced NF-kappaB: a possible connection to blood pressure control?Biological relevance of Hsp90-binding immunophilins in cancer development and treatment.Conformational Dynamics in FKBP Domains: Relevance to Molecular Signaling and Drug DesignHSP90AB1: Helping the good and the bad.Positive feedback within a kinase signaling complex functions as a switch mechanism for NF-κB activation.NF-κB p65 recruited SHP regulates PDCD5-mediated apoptosis in cancer cells.Checks and balances: The glucocorticoid receptor and NFĸB in good times and bad.Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-κB noncanonical and canonical pathway activationReduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.Clathrin complexes with the inhibitor kappa B kinase signalosome: imaging the interactome.The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.The prospect of FKBP51 as a drug target.Interactome analysis of transforming growth factor-β-activated kinase 1 in Helicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37.The Therapeutic Strategy of HDAC6 Inhibitors in Lymphoproliferative Disease
P2860
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P2860
Signal responsiveness of IkappaB kinases is determined by Cdc37-assisted transient interaction with Hsp90.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Signal responsiveness of Ikapp ...... nsient interaction with Hsp90.
@en
type
label
Signal responsiveness of Ikapp ...... nsient interaction with Hsp90.
@en
prefLabel
Signal responsiveness of Ikapp ...... nsient interaction with Hsp90.
@en
P2093
P2860
P356
P1476
Signal responsiveness of Ikapp ...... nsient interaction with Hsp90.
@en
P2093
Albrecht Otto
Claus Scheidereit
Eva-Christina Mueller
Meike Broemer
Rudolf Dettmer
Seda Cöl Arslan
P2860
P304
32311-32319
P356
10.1074/JBC.M705785200
P407
P50
P577
2007-08-29T00:00:00Z