Increased virulence of a mouse-adapted variant of influenza A/FM/1/47 virus is controlled by mutations in genome segments 4, 5, 7, and 8.
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Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genesH5N1 vaccines in humansIL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in miceInfluenza Virus Targets Class I MHC-Educated NK Cells for ImmunoevasionEpisodic evolution mediates interspecies transfer of a murine coronavirusTreating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infectionMolecular determinants of influenza virus pathogenesis in mice.Adaptation of pandemic H1N1 influenza viruses in mice.Mutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to miceIntranasal immunization of baculovirus displayed hemagglutinin confers complete protection against mouse adapted highly pathogenic H7N7 reassortant influenza virusDNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice.A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.Improved and simplified recombineering approach for influenza virus reverse genetics.Characterization of Novel Reassortant Influenza A (H5N2) Viruses Isolated from Poultry in Eastern China, 2015.Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.PB2 and hemagglutinin mutations are major determinants of host range and virulence in mouse-adapted influenza A virusQuantitative proteomic analyses of influenza virus-infected cultured human lung cells.Characterization of an H10N8 influenza virus isolated from Dongting lake wetland.Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation.Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach.Readaptation of a low-virulence influenza H9 escape mutant in mice: the role of changes in hemagglutinin as revealed by site-specific mutagenesisSuppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1.Adaption of seasonal H1N1 influenza virus in mice.Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes.Equine H7N7 influenza A viruses are highly pathogenic in mice without adaptation: potential use as an animal model.Intragenic suppression of a deletion mutation of the nonstructural gene of an influenza A virusExperimental evolution of human influenza virus H3 hemagglutinin in the mouse lung identifies adaptive regions in HA1 and HA2.An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.A single amino acid change in the C-terminal domain of the matrix protein M1 of influenza B virus confers mouse adaptation and virulence.The polymerase acidic protein gene of influenza a virus contributes to pathogenicity in a mouse model.The influenza virus variant A/FM/1/47-MA possesses single amino acid replacements in the hemagglutinin, controlling virulence, and in the matrix protein, controlling virulence as well as growth.Interference is controlled by segment 2 and possibly by segment 8 of the nondefective interfering influenza virus variant A/FM/1/47-MA.Interleukin-15 is critical in the pathogenesis of influenza a virus-induced acute lung injury.Antigenic characterization of an H3N2 swine influenza virus isolated from pigs with proliferative and necrotizing pneumonia in Quebec.A Portrait of the Sialyl Glycan Receptor Specificity of the H10 Influenza Virus Hemagglutinin-A Picture of an Avian Virus on the Verge of Becoming a Pandemic?Adaptive Mutations in Influenza A/California/07/2009 Enhance Polymerase Activity and Infectious Virion Production.
P2860
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P2860
Increased virulence of a mouse-adapted variant of influenza A/FM/1/47 virus is controlled by mutations in genome segments 4, 5, 7, and 8.
description
1990 nî lūn-bûn
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1990年の論文
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1990年学术文章
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1990年学术文章
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1990年学术文章
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1990年学术文章
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1990年学术文章
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1990年學術文章
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1990年學術文章
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1990年學術文章
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name
Increased virulence of a mouse ...... enome segments 4, 5, 7, and 8.
@en
type
label
Increased virulence of a mouse ...... enome segments 4, 5, 7, and 8.
@en
prefLabel
Increased virulence of a mouse ...... enome segments 4, 5, 7, and 8.
@en
P2860
P1433
P1476
Increased virulence of a mouse ...... enome segments 4, 5, 7, and 8.
@en
P2093
P2860
P304
P407
P577
1990-09-01T00:00:00Z