The enhancing effects of the light chain on heavy chain secretion in split delivery of factor VIII gene.
about
Gene therapy for hemophiliaCharacterization of genome integrity for oversized recombinant AAV vector.Advancements in gene transfer-based therapy for hemophilia A.Efficient production of dual recombinant adeno-associated viral vectors for factor VIII deliveryProteasome inhibitors enhance gene delivery by AAV virus vectors expressing large genomes in hemophilia mouse and dog models: a strategy for broad clinical application.Protein replacement therapy and gene transfer in canine models of hemophilia A, hemophilia B, von willebrand disease, and factor VII deficiency.Advances in Gene Delivery Systems.Light chain of factor VIII is sufficient for accelerating cleavage of von Willebrand factor by ADAMTS13 metalloprotease.Engineering Factor Viii for Hemophilia Gene Therapy.Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variantComplete correction of hemophilia A with adeno-associated viral vectors containing a full-size expression cassette.Evaluation of the biological differences of canine and human factor VIII in gene delivery: implications in human hemophilia treatment.Enhanced factor VIII heavy chain for gene therapy of hemophilia ALiver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia.Protein trans-splicing based dual-vector delivery of the coagulation factor VIII gene.Protein trans-splicing as a means for viral vector-mediated in vivo gene therapy.Enhanced plasma factor VIII activity in mice via cysteine mutation using dual vectors.Inter-chain disulfide bond improved protein trans-splicing increases plasma coagulation activity in C57BL/6 mice following portal vein FVIII gene delivery by dual vectors.
P2860
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P2860
The enhancing effects of the light chain on heavy chain secretion in split delivery of factor VIII gene.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The enhancing effects of the l ...... delivery of factor VIII gene.
@en
type
label
The enhancing effects of the l ...... delivery of factor VIII gene.
@en
prefLabel
The enhancing effects of the l ...... delivery of factor VIII gene.
@en
P2093
P2860
P356
P1433
P1476
The enhancing effects of the l ...... delivery of factor VIII gene.
@en
P2093
Fuxiang Zhu
Glenn F Pierce
Hongli Wang
Jennifer Zhao
Jinhui Wang
Lingxia Chen
Qiulan Ding
Rita Sarkar
P2860
P304
P356
10.1038/SJ.MT.6300268
P50
P577
2007-07-24T00:00:00Z