Cholesterol sensitivity of endogenous and myristoylated Akt.
about
The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1Lipid metabolic reprogramming in cancer cellsAn Automated High-throughput Array Microscope for Cancer Cell Mechanics.Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic diseaseCeramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine.Rapid preparation of nuclei-depleted detergent-resistant membrane fractions suitable for proteomics analysis.Cluster analysis of insulin action in adipocytes reveals a key role for Akt at the plasma membraneDissecting the mechanism of insulin resistance using a novel heterodimerization strategy to activate Akt.Cholesterol and benign prostate disease.Mammary tumor growth and pulmonary metastasis are enhanced in a hyperlipidemic mouse model.Induction of apoptosis by the ginsenoside Rh2 by internalization of lipid rafts and caveolae and inactivation of Akt.Molecular genetics of prostate cancer: new prospects for old challengesThe bladder tumor suppressor protein TERE1 (UBIAD1) modulates cell cholesterol: implications for tumor progression.The response of the prostate to circulating cholesterol: activating transcription factor 3 (ATF3) as a prominent node in a cholesterol-sensing networkOSU-T315: a novel targeted therapeutic that antagonizes AKT membrane localization and activation of chronic lymphocytic leukemia cellsCell-type-specific regulation of raft-associated Akt signaling.The complex interplay between cholesterol and prostate malignancy.Integration of proteomic and transcriptomic profiles identifies a novel PDGF-MYC network in human smooth muscle cells.GC-MS Based Plasma Metabolomics for Identification of Candidate Biomarkers for Hepatocellular Carcinoma in Egyptian CohortMultiple-Localization and Hub Proteins.Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease.Monitoring of high-density lipoprotein cholesterol level is predictive of EGFR mutation and efficacy of EGFR-TKI in patients with advanced lung adenocarcinoma.Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1.Plasma membrane cholesterol content affects nitric oxide diffusion dynamics and signalingG-CSF activation of AKT is not sufficient to prolong neutrophil survivalSpatiotemporal analysis of differential Akt regulation in plasma membrane microdomainsAkt signaling dynamics in plasma membrane microdomains visualized by FRET-based reporters.The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes.The activity of the epithelial sodium channels is regulated by caveolin-1 via a Nedd4-2-dependent mechanism.Vitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLPP1.The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics.Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.LDL cholesterol counteracts the antitumour effect of tyrosine kinase inhibitors against renal cell carcinoma.Statin derivatives as therapeutic agents for castration-resistant prostate cancer.Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin responseLipid rafts couple store-operated Ca2+ entry to constitutive activation of PKB/Akt in a Ca2+/calmodulin-, Src- and PP2A-mediated pathway and promote melanoma tumor growth.Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells.Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.Two different PDGF beta-receptor cohorts in human pericytes mediate distinct biological endpoints.Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation.
P2860
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P2860
Cholesterol sensitivity of endogenous and myristoylated Akt.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Cholesterol sensitivity of endogenous and myristoylated Akt.
@en
type
label
Cholesterol sensitivity of endogenous and myristoylated Akt.
@en
prefLabel
Cholesterol sensitivity of endogenous and myristoylated Akt.
@en
P2093
P1433
P1476
Cholesterol sensitivity of endogenous and myristoylated Akt.
@en
P2093
Bekir Cinar
Dolores Di Vizio
Jayoung Kim
Keith R Solomon
Kelly Boucher
Michael R Freeman
Nishit K Mukhopadhyay
Rosalyn M Adam
P304
P356
10.1158/0008-5472.CAN-07-0288
P407
P577
2007-07-01T00:00:00Z