Development of anti-pp60src serum with antigen produced in Escherichia coli.
about
Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.Differential response to retinoic acid of Syrian hamster embryo fibroblasts expressing v-src or v-Ha-ras oncogenesNeoplastic transformation of normal and carcinogen-induced preneoplastic Syrian hamster embryo cells by the v-src oncogene.Amino acid alterations within a highly conserved region of the Rous sarcoma virus src gene product pp60src inactivate tyrosine protein kinase activity.Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteinsAssociation of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation.Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stabilityInhibition of the tyrosine kinase activity of v-src, v-fgr, and v-yes gene products by a monoclonal antibody which binds both amino and carboxy peptide fragments of pp60v-src.Site-directed point mutation in the src gene oF rous sarcoma virus results in an inactive src gene product.Isolation and partial characterization of a monoclonal antibody to the Rous sarcoma virus transforming protein pp60src.A fission-yeast gene encoding a protein with features of protein-tyrosine-phosphatasesNonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblastsA Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases.c-src gene product in developing rat brain is enriched in nerve growth cone membranesEvolutionary expression of the neuronal form of the src protein in the brain.A protein kinase antigenically related to pp60v-src possibly involved in yeast cell cycle control: positive in vivo regulation by sterol.Highly specific antibody to Rous sarcoma virus src gene product recognizes nuclear and nucleolar antigens in human cellsHighly specific antibody to Rous sarcoma virus src gene product recognizes a novel population of pp60v-src and pp60c-src molecules.Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblastsExpression of Rous sarcoma virus transforming protein pp60v-src in Saccharomyces cerevisiae cellsImmunological characterization of proteins detected by phosphotyrosine antibodies in cells transformed by Rous sarcoma virus.Characterization of pp60src phosphorylation in vitro in Rous sarcoma virus-transformed cell membranes.Low level of cellular protein phosphorylation by nontransforming overproduced p60c-srcOverexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells.Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60c-src relative to pp60v-src.Lack of induction of neuroretinal cell proliferation by Rous sarcoma virus variants that carry the c-src geneDevelopment and characterization of antisera specific for amino- and carboxy-terminal regions of pp60src.Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma virusesTransformation of NIH 3T3 cells by cotransfection with c-src and nuclear oncogenes.Expression of the chicken c-src gene in COS cellsMutation of a termination codon affects src initiation.Phosphatidylinositol kinase activities in normal and Rous sarcoma virus-transformed cells.Intracellular localization and processing of pp60v-src proteins expressed by two distinct temperature-sensitive mutants of Rous sarcoma virus.A single point mutation has pleiotropic effects on pp60v-src function.Forms of pp60v-src isolated from Rous sarcoma virus-transformed cells.Neural tissues express high levels of the cellular src gene product pp60c-src.
P2860
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P2860
Development of anti-pp60src serum with antigen produced in Escherichia coli.
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
1983年论文
@zh
1983年论文
@zh-cn
name
Development of anti-pp60src serum with antigen produced in Escherichia coli.
@en
type
label
Development of anti-pp60src serum with antigen produced in Escherichia coli.
@en
prefLabel
Development of anti-pp60src serum with antigen produced in Escherichia coli.
@en
P2860
P1433
P1476
Development of anti-pp60src serum with antigen produced in Escherichia coli
@en
P2093
R L Erikson
T M Gilmer
P2860
P304
P407
P577
1983-01-01T00:00:00Z