Gating and flickery block differentially affected by rubidium in homomeric KCNQ1 and heteromeric KCNQ1/KCNE1 potassium channels.
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On the structural basis of modal gating behavior in K+ channelsStructural basis of slow activation gating in the cardiac I Ks channel complexTwo open states and rate-limiting gating steps revealed by intracellular Na+ block of human KCNQ1 and KCNQ1/KCNE1 K+ channelsA multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential.Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes.Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T).Structural requirements for differential sensitivity of KCNQ K+ channels to modulation by Ca2+/calmodulin.A computational model of the human left-ventricular epicardial myocyte.Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.Probing binding sites and mechanisms of action of an I(Ks) activator by computations and experiments.Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channelComputational biology in the study of cardiac ion channels and cell electrophysiology.An inactivation gate in the selectivity filter of KCNQ1 potassium channels.Relationship between pore occupancy and gating in BK potassium channels.Na+ block and permeation in a K+ channel of known structureVoltage-Dependent Gating: Novel Insights from KCNQ1 Channels.KCNE4 and KCNE5: K(+) channel regulation and cardiac arrhythmogenesis.Ionic permeation and conduction properties of neuronal KCNQ2/KCNQ3 potassium channels.Role of the S6 C-terminus in KCNQ1 channel gating.Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome.Single-channel basis for conductance increase induced by isoflurane in Shaker H4 IR K(+) channels.Persistent sodium current is a target for cAMP-induced neuronal plasticity in a state-setting modulatory interneuron.Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening.KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions.Tight coupling of rubidium conductance and inactivation in human KCNQ1 potassium channels.Mechanisms Underlying the Dual Effect of Polyunsaturated Fatty Acid Analogs on Kv7.1
P2860
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P2860
Gating and flickery block differentially affected by rubidium in homomeric KCNQ1 and heteromeric KCNQ1/KCNE1 potassium channels.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Gating and flickery block diff ...... CNQ1/KCNE1 potassium channels.
@en
type
label
Gating and flickery block diff ...... CNQ1/KCNE1 potassium channels.
@en
prefLabel
Gating and flickery block diff ...... CNQ1/KCNE1 potassium channels.
@en
P2860
P1433
P1476
Gating and flickery block diff ...... CNQ1/KCNE1 potassium channels.
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(00)76586-6
P407
P577
2000-01-01T00:00:00Z