Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.
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Crystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentationThe sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor functionChanges in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restrictionLoss of IL-15 receptor α alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles.Serum and muscle interleukin-15 levels decrease in aging mice: correlation with declines in soluble interleukin-15 receptor alpha expressionIntron 4 containing novel GABAB1 isoforms impair GABAB receptor functionActivated T cells secrete an alternatively spliced form of common γ-chain that inhibits cytokine signaling and exacerbates inflammationIL-7 in human health and disease.Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T-cell function in cisInterleukin-15, IL-15 Receptor-Alpha, and Obesity: Concordance of Laboratory Animal and Human Genetic StudiesAltered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics.Production of bioactive soluble interleukin-15 in complex with interleukin-15 receptor alpha from a conditionally-replicating oncolytic HSV-1Porcine reproductive and respiratory syndrome virus induces interleukin-15 through the NF-κB signaling pathwayAn intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2Design and characterization of a protein superagonist of IL-15 fused with IL-15Rα and a high-affinity T cell receptorMolecular mechanisms of soluble cytokine receptor generation.The anticancer immune response: indispensable for therapeutic success?The IL-15 receptor {alpha} chain cytoplasmic domain is critical for normal IL-15Ralpha function but is not required for trans-presentationOversecretion of interleukin-15 from skeletal muscle reduces adiposityInterleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancerAccumulation of uterine CD16(-) natural killer (NK) cells: friends, foes, or Jekyll-and-Hyde relationship for the conceptus?Role of IL-15 and IL-21 in viral immunity: applications for vaccines and therapies.Trans-presentation: a novel mechanism regulating IL-15 delivery and responses.Interleukin and interleukin receptor diversity: role of alternative splicing.Enhancement of the inhibitory effect of an IL-15 antagonist peptide by alanine scanning.How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha.Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity.Identification of a potent anti-IL-15 antibody with opposing mechanisms of action in vitro and in vivo.Neutralizing IL-21 and IL-15 inhibits pro-inflammatory cytokine production in rheumatoid arthritis.German research centre widens misconduct probe
P2860
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P2860
Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Soluble Interleukin IL-15Ralph ...... nctional complexes with IL-15.
@en
type
label
Soluble Interleukin IL-15Ralph ...... nctional complexes with IL-15.
@en
prefLabel
Soluble Interleukin IL-15Ralph ...... nctional complexes with IL-15.
@en
P2093
P2860
P356
P1476
Soluble Interleukin IL-15Ralph ...... nctional complexes with IL-15.
@en
P2093
Elena Bulanova
Erwin Duitman
Hans Krause
Norbert Reiling
Rene Rückert
Silvia Bulfone-Paus
Vadim Budagian
Zane Orinska
P2860
P304
13167-13179
P356
10.1074/JBC.M610036200
P407
P577
2007-02-27T00:00:00Z