Overexpression of the heat-shock protein 70 is associated to imatinib resistance in chronic myeloid leukemia.
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The human HSP70 family of chaperones: where do we stand?Modulation of Akt and ERK1/2 pathways by resveratrol in chronic myelogenous leukemia (CML) cells results in the downregulation of Hsp70A natural-like synthetic small molecule impairs bcr-abl signaling cascades and induces megakaryocyte differentiation in erythroleukemia cellsDevelopment and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells.The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells.The derivation of diagnostic markers of chronic myeloid leukemia progression from microarray data.Differential heat shock protein localization in chronic lymphocytic leukemiaAnti-leukemia activity of a Hsp70 inhibitor and its hybrid moleculesHeat shock protein 70 (hsp70) as an emerging drug target.Circulating heat shock protein 70 and progression in patients with chronic myeloid leukemia.Induction of high-titer IgG antibodies against multiple leukemia-associated antigens in CML patients with clinical responses to K562/GVAX immunotherapy.Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditionsThe Chemical Biology of Molecular Chaperones--Implications for Modulation of ProteostasisComparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disordersMycophenolic Acid overcomes imatinib and nilotinib resistance of chronic myeloid leukemia cells by apoptosis or a senescent-like cell cycle arrest.The HSP70 family and cancerTargeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3.Pharmacological targeting of the Hsp70 chaperone.The heat shock proteins as targets for radiosensitization and chemosensitization in cancerHeat shock proteins in multiple myelomaSuppression of heat shock protein 70 by siRNA enhances the antitumor effects of cisplatin in cultured human osteosarcoma cells.Targeting Hsp70: A possible therapy for cancer.Dual targeting of heat shock proteins 90 and 70 promotes cell death and enhances the anticancer effect of chemotherapeutic agents in bladder cancerCAMKIIγ, HSP70 and HSP90 transcripts are differentially expressed in chronic myeloid leukemia cells from patients with resistant mutated disease.Cellular and Molecular Targets of Resveratrol on Lymphoma and Leukemia Cells.Proteomic analysis of an imatinib-resistant K562 cell line highlights opposing roles of heat shock cognate 70 and heat shock 70 proteins in resistance.BCR-ABL1-induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemia.Analysis of cell surface and relative gene expression of heat shock protein 70 in human leukemia cell lines.Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia.Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis.Quantitative- and phospho-proteomic analysis of the yeast response to the tyrosine kinase inhibitor imatinib to pharmacoproteomics-guided drug line extension.Hsp70: A Cancer Target Inside and Outside the Cell.Consequences of heat shock protein 72 (Hsp72) expression and activity on stress-induced apoptosis in CD30+ NPM-ALK+ anaplastic large-cell lymphomas.Could Upregulated Hsp70 Protein Compensate for the Hsp90-Silence-Induced Cell Death in Glioma Cells?
P2860
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P2860
Overexpression of the heat-shock protein 70 is associated to imatinib resistance in chronic myeloid leukemia.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Overexpression of the heat-sho ...... e in chronic myeloid leukemia.
@en
type
label
Overexpression of the heat-sho ...... e in chronic myeloid leukemia.
@en
prefLabel
Overexpression of the heat-sho ...... e in chronic myeloid leukemia.
@en
P2093
P2860
P921
P356
P1433
P1476
Overexpression of the heat-sho ...... e in chronic myeloid leukemia.
@en
P2093
Claverol S
Guyonnet-Duperat V
Moreau-Gaudry F
Pasquet JM
P2860
P2888
P304
P356
10.1038/SJ.LEU.2404463
P577
2006-11-16T00:00:00Z
P5875
P6179
1029837227