Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals.
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SOCS, inflammation, and cancerThe role of suppressors of cytokine signalling in human neoplasmsSignal transducer and activator of transcription 5A/B in prostate and breast cancersQuantification of PRL/Stat5 signaling with a novel pGL4-CISH reporterHigher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer.SOCS3 deletion in T lymphocytes suppresses development of chronic ocular inflammation via upregulation of CTLA-4 and expansion of regulatory T cells.A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines.In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.Loss of expression and function of SOCS3 is an early event in HNSCC: altered subcellular localization as a possible mechanism involved in proliferation, migration and invasionThe iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway.Overexpression of miR -155 promotes proliferation and invasion of human laryngeal squamous cell carcinoma via targeting SOCS1 and STAT3.Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer.Suppressor of cytokine signaling (SOCS) genes are silenced by DNA hypermethylation and histone deacetylation and regulate response to radiotherapy in cervical cancer cells.Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxelStat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.Estrogen accelerates the resolution of inflammation in macrophagic cells.Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomasLoss of annexin A1 disrupts normal prostate glandular structure by inducing autocrine IL-6 signaling.Dysregulation of SOCS-Mediated Negative Feedback of Cytokine Signaling in Carcinogenesis and Its Significance in Cancer Treatment.CD8+ T cells promote proliferation of benign prostatic hyperplasia epithelial cells under low androgen level via modulation of CCL5/STAT5/CCND1 signaling pathway.Interleukin-6: a multifunctional targetable cytokine in human prostate cancer.Enhanced expression of suppresser of cytokine signaling 3 inhibits the IL-6-induced epithelial-to-mesenchymal transition and cholangiocarcinoma cell metastasis.miR-17-5p promotes proliferation by targeting SOCS6 in gastric cancer cells.Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulates human chondrocyte function.Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway.Development of IFN-gamma resistance is associated with attenuation of SOCS genes induction and constitutive expression of SOCS 3 in melanoma cells.The inhibition of stat5 by a Peptide aptamer ligand specific for the DNA binding domain prevents target gene transactivation and the growth of breast and prostate tumor cellsRole of SOCS-1 Gene on Melanoma Cell Growth and Tumor Development.Elongin B/C recruitment regulates substrate binding by CIS.Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration.Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion.The Expression Levels of IL-4/IL-13/STAT6 Signaling Pathway Genes and SOCS3 Could Help to Differentiate the Histopathological Subtypes of Non-Small Cell Lung Carcinoma
P2860
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P2860
Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Expression of SOCS1 and SOCS3 ...... ine and growth factor signals.
@en
type
label
Expression of SOCS1 and SOCS3 ...... ine and growth factor signals.
@en
prefLabel
Expression of SOCS1 and SOCS3 ...... ine and growth factor signals.
@en
P2093
P2860
P356
P1433
P1476
Expression of SOCS1 and SOCS3 ...... kine and growth factor signals
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209993
P407
P577
2006-09-25T00:00:00Z
P5875
P6179
1044296396