Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer. - Wikidata - wikimedia - TriplyDB

Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

http://www.wikidata.org/entity/Q35906313

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GREB1 functions as a growth promoter and is modulated by IL6/STAT3 in breast cancer HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis Targeting the tumor microenvironment: JAK-STAT3 signaling Targeting SH2 domains in breast cancer Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway AZD1480 blocks growth and tumorigenesis of RET- activated thyroid cancer cell lines Developmental therapeutics for inflammatory breast cancer: Biology and translational directions NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET)STAT3 negatively regulates thyroid tumorigenesis Brevilin A, a novel natural product, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells STAT3 can be activated through paracrine signaling in breast epithelial cells.Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation.The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors.Discovery of pathway biomarkers from coupled proteomics and systems biology methods Antitumor efficacy of the anti-interleukin-6 (IL-6) antibody siltuximab in mouse xenograft models of lung cancer.Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer Roles for inflammation and regulatory T cells in colon cancer.Cancer inflammation and regulatory T cells.Stat3 mediates expression of autotaxin in breast cancer Global gene expression analysis of the interaction between cancer cells and osteoblasts to predict bone metastasis in breast cancer EGCG enhances the therapeutic potential of gemcitabine and CP690550 by inhibiting STAT3 signaling pathway in human pancreatic cancer.Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses Therapeutic CK2 inhibition attenuates diverse prosurvival signaling cascades and decreases cell viability in human breast cancer cells.Clinical implications of phosphorylated STAT3 expression in De Novo diffuse large B-cell lymphoma The cytokine IL-6 reactivates breast stromal fibroblasts through transcription factor STAT3-dependent up-regulation of the RNA-binding protein AUF1.MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells.Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis Oral administration of penta-O-galloyl-β-D-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 inhibition.Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells.RhoC regulates cancer stem cells in head and neck squamous cell carcinoma by overexpressing IL-6 and phosphorylation of STAT3.Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer.RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch.Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.Antagonism of the Stat3-Stat3 protein dimer with salicylic acid based small molecules.The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.

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Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

http://www.wikidata.org/entity/Q35906313

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Stat3 is tyrosine-phosphorylat ...... nase pathway in breast cancer.

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Stat3 is tyrosine-phosphorylat ...... nase pathway in breast cancer.

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Stat3 is tyrosine-phosphorylat ...... nase pathway in breast cancer.

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Stat3 is tyrosine-phosphorylat ...... nase pathway in breast cancer.

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Breast Cancer Research

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Stat3 is tyrosine-phosphorylat ...... inase pathway in breast cancer

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Jacqueline F Bromberg

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Kenneth Leslie

http://www.w3.org/2001/XMLSchema#string

Marjan Berishaj

http://www.w3.org/2001/XMLSchema#string

Simi Ahmed

http://www.w3.org/2001/XMLSchema#string

Sizhi Paul Gao

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William Bornmann

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William L Gerald

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P2860

Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis

An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells

Genes that mediate breast cancer metastasis to lung

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

STATs and gene regulation

The STATs of cancer--new molecular targets come of age

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells.

JAK protein kinase inhibitors.

Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells.

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10.1186/BCR1680

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3

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9

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Hikmat Al-Ahmadie

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phosphorylation

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1929096

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